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Adjusted-Dose Warfarin versus Aspirin for Preventing Stroke in Patients with Atrial Fibrillation

Robert G. Hart, MD; Lesly A. Pearce, MS; and Maria I. Aguilar, MD
[+] Article, Author, and Disclosure Information

From the University of Texas Health Science Center, San Antonio, TX 78229-3900; Minot, ND 58703; and Mayo Clinic Scottsdale, Phoenix, AZ 85054.

Potential Financial Conflicts of Interest: None disclosed.

Ann Intern Med. 2007;147(8):590-592. doi:10.7326/0003-4819-147-8-200710160-00018
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Relative effects of warfarin versus antiplatelet agents on all strokes from randomized trials in patients with atrial fibrillation.

ACTIVE-W = Atrial fibrillation Clopidogrel Trial with Irbesartan for prevention of Vascular Events; AFASAK = Atrial Fibrillation, ASpirin, AntiKoagulation; ATAFS = Antithrombotic Therapy in Atrial Fibrillation Study; BAFTA = Birmingham Atrial Fibrillation Treatment of the Aged; EAFT = European Atrial Fibrillation Trial; NASPEAF = NAtional Study for Prevention of Embolism in Atrial Fibrillation; PATAF = Prevention of Arterial Thromboembolism in Atrial Fibrillation; SIFA = Studio Italiano Fibrillazione Atriale; SPAF = Stroke Prevention in Atrial Fibrillation. *The Athens Trial (13) and the Warfarin vs. Aspirin for Stroke Prevention in Octogenarians (14) trial are not shown because the 95% CIs spanned beyond the width of the figure, but their results are included in the meta-analyses in the Table.

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