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Overanticoagulation with Coumarin and Cutaneous Azole Therapy

Jean-François Alexandra, MD; Eric Pautas, MD; Isabelle Gouin-Thibault, PhD; Virginie Siguret, MD; and Marie-Anne Loriot, PhD
[+] Article, Author, and Disclosure Information

From Hôpital Charles Foix, Ivry-sur-Seine 94205, France, and INSERM U775, Université Paris Descartes, 75006 Paris, France.

Potential Financial Conflicts of Interest: None disclosed.

Ann Intern Med. 2008;148(8):633-635. doi:10.7326/0003-4819-148-8-200804150-00025
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Time course of international normalized ratios (INRs) and characteristics of coumarin and cutaneous azole therapies in the 6 patients with INRs greater than 5.0.

Day 0 was defined as the first day with INR >5.0. Vitamin K administration (dosages and routes) are shown. IV = intravenous.

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