0

The full content of Annals is available to subscribers

Subscribe/Learn More  >
Editorials |

Diagnostic Test Accuracy and Clinical Decision Making

John Cornell, PhD, Associate Editor; Cynthia D. Mulrow, MD, MSc, Deputy Editor; and A. Russell Localio, PhD, Associate Editor
[+] Article and Author Information

Potential Financial Conflicts of Interest: None disclosed.

Corresponding Author: John E. Cornell, PhD, Department of Epidemiology and Biostatistics, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900.


Ann Intern Med. 2008;149(12):904-906. doi:10.7326/0003-4819-149-12-200812160-00011
Text Size: A A A

Selecting a diagnostic test is a complex and sometimes bewildering task. Systematic reviews of diagnostic test accuracy provide only some of the essential information that physicians need. Choice of a diagnostic test is embedded within a dynamic multistage screening and decision-making context in which past clinical assessments and review of personal and family medical history determine the need for testing. For diagnostic tests, it is important to understand not only the test characteristics, such as sensitivity and specificity, but also the relative benefits and harms from actions in response to test results for subgroups of patients and the individual patient. Authors of systematic reviews of diagnostic test accuracy need to see beyond reporting the summary receiver-operating characteristic (ROC) curves and summary measures of diagnostic accuracy. By examining the expected downstream harms and benefits of positive and negative test results, authors can link diagnostic accuracy to clinical decision making.

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Letters

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Comments

Submit a Comment
Submit a Comment

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.

Toolkit

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Advertisement
Related Articles
Journal Club
Topic Collections
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.
(Required)
(Required)