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Is There a Proven Link Between Anal Cancer Screening and Reduced Morbidity or Mortality?

Kenneth A. Katz, MD, MSc, MSCE; Christina A. Clarke, PhD, MPH; Kyle T. Bernstein, PhD, ScM; Mitchell H. Katz, MD; and Jeffrey D. Klausner, MD, MPH
[+] Article, Author, and Disclosure Information

From Centers for Disease Control and Prevention, Atlanta, GA 30333; Northern California Cancer Center, Fremont, CA 94538; and San Francisco Department of Public Health, San Francisco, CA 94103.

Note: The cancer incidence data used in this study were supported by the California Department of Public Health as part of the statewide cancer reporting program mandated by California Health and Safety Code Section 103885; the National Cancer Institute's Surveillance, Epidemiology and End Results Program under contract N01-PC-35136 awarded to the Northern California Cancer Center, contract N01-PC-35139 awarded to the University of Southern California, and contract N01-PC-54404 awarded to the Public Health Institute; and the Centers for Disease Control and Prevention's National Program of Cancer Registries, under agreement 1U58DP00807-01 awarded to the Public Health Institute. The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the State of California, the California Department of Public Health, the National Cancer Institute, and the Centers for Disease Control and Prevention or their contractors and subcontractors. Endorsement by any of those agencies is not intended nor should be inferred.

Potential Financial Conflicts of Interest: None disclosed.

Ann Intern Med. 2009;150(4):283-284. doi:10.7326/0003-4819-150-4-200902170-00020
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Age-adjusted incidence of AIN 3 and invasive squamous cell carcinoma of the anus* among non-Hispanic white male residents of San Francisco County, 1988–2005.

AIN 3 = anal intraepithelial neoplasia 3 (including in situ carcinoma).

* Anal cancer was defined by using International Classification of Diseases, Oncology, 3rd edition, site codes C210–C212 and C218; AIN 3 by histology code 8077; in situ squamous cell carcinoma by histology codes 8010, 8051–8078, 8081; and invasive squamous cell carcinoma by histology codes 8010, 8051–8076, and 8078.

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