The full content of Annals is available to subscribers

Subscribe/Learn More  >
Editorials |

Evaluating the President's Emergency Plan for AIDS Relief: Time to Scale It Up

Robert Gross, MD, MSCE; and Gregory Bisson, MD, MSCE
[+] Article, Author, and Disclosure Information

From Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104.

Potential Financial Conflicts of Interest:Grants received: R. Gross (National Institutes of Health [National Institute of Mental Health and National Institute of Allergy and Infectious Diseases], Agency for Healthcare Research and Quality, Abbott Laboratories, Bristol-Myers Squibb, Doris Duke Charitable Foundation), G.P. Bisson (National Institutes of Health [National Institute of Allergy and Infectious Diseases], Doris Duke Charitable Foundation). Other: Drs. Gross and Bisson conduct research in Botswana under the auspices of the Botswana-UPenn Partnership, which receives support from PEPFAR to provide care to HIV-infected persons in Botswana. Neither author receives funds from PEPFAR.

Requests for Single Reprints: Robert Gross, MD, MSCE, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 8th Floor, Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104-6021; e-mail, grossr@mail.med.upenn.edu.

Current Author Addresses: Drs. Gross and Bisson: Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 8th Floor, Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104-6021.

Ann Intern Med. 2009;150(10):727-728. doi:10.7326/0003-4819-150-10-200905190-00012
Text Size: A A A

In 2003, the U.S. government embarked on the largest public health program ever created by 1 country to fight a single disease: HIV/AIDS. The nucleus of the program, framed in the context of urgent need, was aptly named the President's Emergency Plan for AIDS Relief (PEPFAR). The initial goals of PEPFAR were to confront HIV and AIDS on multiple fronts by scaling up services to prevent vertical and horizontal HIV transmission, to provide medical therapy through the procurement and distribution of antiretroviral and ancillary drugs, and to support care for HIV-uninfected persons whose lives had become unstable because of HIV/AIDS. Although PEPFAR money flows to more than 120 nations, 15 focus countries, 12 of which are in Africa, get most of the money. From the beginning, PEPFAR has been a goal-driven program, with initial 5-year performance targets of providing antiretroviral therapy to 2 million people, preventing 7 million new HIV infections, and delivering supportive care to 10 million people affected directly or indirectly by HIV/AIDS (1). Initially conceived as a moral imperative, PEPFAR was historic in both its scale and the compressed time scale for meeting its objectives.

First Page Preview

View Large
First page PDF preview





Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $32.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
Topic Collections
PubMed Articles
[HIV infection : Test and treatment]. Internist (Berl) Published online Jul 1, 2016;
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.