Abnormal cholesterol levels put people at risk for health problems, including heart attack and stroke. Higher levels of “good cholesterol,” known as high-density lipoprotein (HDL), protect blood vessels against blockage by fatty deposits, whereas “bad cholesterol,” known as low-density lipoprotein (LDL), worsens fatty deposits. Treatment of cholesterol problems with medication is recommended for people at high risk for these health problems. Statins are a class of medications that are very effective at lowering LDL cholesterol levels to the desired range, and they have had few side effects. However, in some people, statins can cause muscle pain (myalgias) and weakness. In most cases, people experience muscle pain without muscle damage. If there is muscle damage, the condition is called myopathy.