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Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.
SUMMARIES FOR PATIENTS
The Effects of a Smoking Cessation Program on Long-Term Survival in Smokers with Mild Lung Disease
15 February 2005 | Volume 142 Issue 4 | Page I-12
Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians.
The summary below is from the full report titled "The Effects of a Smoking Cessation Intervention on 14.5-Year Mortality. A Randomized Clinical Trial." It is in the 15 February 2005 issue of Annals of Internal Medicine (volume 142, pages 233-239). The authors are N.R. Anthonisen, M.A. Skeans, R.A. Wise, J. Manfreda, R.E. Kanner, and J.E. Connett, PhD, for the Lung Health Study Research Group.
What is the problem and what is known about it so far?
Smoking cigarettes increases a person's risk for many health problems, including cancer, heart disease, and lung disease. Several studies have shown many benefits for smokers who quit. However, no studies have proven that smoking cessation programs lead to better long-term survival. Chronic obstructive pulmonary disease (COPD), a disease of the air sacs and air passages of the lungs, is one of the many health problems to which smoking contributes. People with COPD are short of breath and sometimes cough and wheeze. Damage to the lungs and symptoms slowly worsen over time, especially if people do not stop smoking. Smoking cessation is particularly important for people with COPD who want to slow the worsening of their disease.
Why did the researchers do this particular study?
To see if a smoking cessation program improved long-term survival in people with mild COPD.
Who was studied?
5887 middle-aged people with early COPD (they had abnormal results on lung tests but did not consider themselves to be sick). The people were participating in a large study called the Lung Health Study, which examined whether a smoking cessation program and treatment with a drug called ipratropium could prevent worsening of disease in people with mild COPD.
How was the study done?
The researchers assigned participants to attend a special smoking cessation program or to receive usual care. The smoking cessation program included 12 two-hour group sessions over a 10-week period. The sessions used behavior modification and nicotine gum. The researchers followed study participants for up to 14.5 years and collected information about smoking status and death from heart disease, lung disease, cancer, or any other cause.
What did the researchers find?
After 5 years, 21.7% of the people in the special program had completely stopped smoking compared with only 5.4% of people in the usual care group. However, despite the relatively small proportion of participants who stopped smoking, the death rate in the group that received the smoking cessation program was lower, by about 15%, than the rate in the group that received usual care. Not surprisingly, the benefit with respect to survival was largest among participants who actually stopped smoking: Their death rates were 46% lower than those of the people who continued to smoke.
What were the limitations of the study?
This study involved only people with early signs of COPD on lung tests. It is unknown whether the survival benefits of a smoking cessation program would also exist among people without such signs.
What are the implications of the study?
Intensive smoking cessation programs can improve long-term survival, even when successful in only a minority of patients.
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|
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|
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|
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|
|
|
|
 |
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|
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|
|
|
|
|
|
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|
|
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|
 |
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|
|
|
|
 |
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
 M Bednarek, J Maciejewski, M Wozniak, P Kuca, and J Zielinski Prevalence, severity and underdiagnosis of COPD in the primary care setting Thorax, May 1, 2008; 63(5): 402 - 407. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. H Au Use of {beta} blockers in patients with COPD Thorax, April 1, 2008; 63(4): 296 - 298. [Full Text] [PDF]
|
|
|
|
|
|
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|
|
|
|
 |
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
 M. Poulain, M. Doucet, V. Drapeau, G. Fournier, A. Tremblay, P. Poirier, and F. Maltais Metabolic and inflammatory profile in obese patients with chronic obstructive pulmonary disease Chronic Respiratory Disease, February 1, 2008; 5(1): 35 - 41. [Abstract] [PDF]
|
|
|
|
 |
|
 A. J. Karter, M. R. Stevens, E. W. Gregg, A. F. Brown, C.-W. Tseng, D. G. Marrero, O. K. Duru, T. L. Gary, J. D. Piette, B. Waitzfelder, et al. Educational Disparities in Rates of Smoking Among Diabetic Adults: The Translating Research Into Action for Diabetes Study Am J Public Health, February 1, 2008; 98(2): 365 - 370. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
P M A Calverley and J A Wedzicha Chronic obstructive pulmonary disease past, present and future Thorax, December 1, 2007; 62(12): 1026 - 1027. [Full Text] [PDF]
|
|
|
|
 |
|
 I. Shrier, J.-F. Boivin, R. J. Steele, R. W. Platt, A. Furlan, R. Kakuma, J. Brophy, and M. Rossignol Should Meta-Analyses of Interventions Include Observational Studies in Addition to Randomized Controlled Trials? A Critical Examination of Underlying Principles Am. J. Epidemiol., November 15, 2007; 166(10): 1203 - 1209. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. M. Stack and A. J. Zillich Implementation of inpatient and outpatient tobacco-cessation programs Am. J. Health Syst. Pharm., October 1, 2007; 64(19): 2074 - 2079. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. M. Calverley Eur. Respir. Rev., September 1, 2007; 16(105): 89 - 90. [Full Text] [PDF]
|
|
|
|
|
|
S. I. Rennard Inflammation in COPD: a link to systemic comorbidities Eur. Respir. Rev., September 1, 2007; 16(105): 91 - 97. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Roche Where current pharmacological therapies fall short in COPD: symptom control is not enough Eur. Respir. Rev., September 1, 2007; 16(105): 98 - 104. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. van den Bemt, T. Schermer, and C. van Weel Rational monitoring of COPD: where do current clinical guidelines stand? Eur. Respir. J., June 1, 2007; 29(6): 1078 - 1081. [Full Text] [PDF]
|
|
|
|
|
|
L. P McGarvey, M. John, J. A Anderson, M. Zvarich, and R. A Wise Ascertainment of cause-specific mortality in COPD: operations of the TORCH Clinical Endpoint Committee Thorax, May 1, 2007; 62(5): 411 - 415. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
 P. M.A. Calverley, J. A. Anderson, B. Celli, G. T. Ferguson, C. Jenkins, P. W. Jones, J. C. Yates, J. Vestbo, and the TORCH investigators Salmeterol and Fluticasone Propionate and Survival in Chronic Obstructive Pulmonary Disease N. Engl. J. Med., February 22, 2007; 356(8): 775 - 789. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
 J. B. Buse, H. N. Ginsberg, G. L. Bakris, N. G. Clark, F. Costa, R. Eckel, V. Fonseca, H. C. Gerstein, S. Grundy, R. W. Nesto, et al. Primary Prevention of Cardiovascular Diseases in People With Diabetes Mellitus: A scientific statement from the American Heart Association and the American Diabetes Association Diabetes Care, January 1, 2007; 30(1): 162 - 172. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
P M A Calverley Caring for the burden of COPD. Thorax, October 1, 2006; 61(10): 831 - 832. [Full Text] [PDF]
|
|
|
|
|
|
D D Sin Inhaled corticosteroids and mortality in COPD Thorax, October 1, 2006; 61(10): 918 - 918. [Full Text] [PDF]
|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
 J.-F. Etter and J. A Stapleton Nicotine replacement therapy for long-term smoking cessation: a meta-analysis. Tob. Control, August 1, 2006; 15(4): 280 - 285. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. J. Kelloff, S. M. Lippman, A. J. Dannenberg, C. C. Sigman, H. L. Pearce, B. J. Reid, E. Szabo, V. C. Jordan, M. R. Spitz, G. B. Mills, et al. Progress in Chemoprevention Drug Development: The Promise of Molecular Biomarkers for Prevention of Intraepithelial Neoplasia and Cancer--A Plan to Move Forward Clin. Cancer Res., June 15, 2006; 12(12): 3661 - 3697. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
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|
|
|
|
 |
|
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|
|
|
|
|
|
D. M. Mannino, G. Watt, D. Hole, C. Gillis, C. Hart, A. McConnachie, G. Davey Smith, M. Upton, V. Hawthorne, D. D. Sin, et al. The natural history of chronic obstructive pulmonary disease. Eur. Respir. J., March 1, 2006; 27(3): 627 - 643. [Full Text] [PDF]
|
|
|
|
|
|
A. Ramirez-Venegas, R. H. Sansores, R. Perez-Padilla, J. Regalado, A. Velazquez, C. Sanchez, and M. E. Mayar Survival of Patients with Chronic Obstructive Pulmonary Disease Due to Biomass Smoke and Tobacco Am. J. Respir. Crit. Care Med., February 15, 2006; 173(4): 393 - 397. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Thom, N. Haase, W. Rosamond, V. J. Howard, J. Rumsfeld, T. Manolio, Z.-J. Zheng, K. Flegal, C. O'Donnell, S. Kittner, et al. Heart Disease and Stroke Statistics--2006 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee Circulation, February 14, 2006; 113(6): e85 - e151. [Full Text] [PDF]
|
|
|
|
|
|
J C Hogg Why does airway inflammation persist after the smoking stops? Thorax, February 1, 2006; 61(2): 96 - 97. [Full Text] [PDF]
|
|
|
|
|
|
B. R. Celli Chronic Obstructive Pulmonary Disease: From Unjustified Nihilism to Evidence-based Optimism. Proceedings of the ATS, January 1, 2006; 3(1): 58 - 65. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D D Sin and S F P Man Skeletal muscle weakness, reduced exercise tolerance, and COPD: is systemic inflammation the missing link? Thorax, January 1, 2006; 61(1): 1 - 3. [Full Text] [PDF]
|
|
|
|
 |
|
 Long-Term Survival After a Smoking-Cessation Intervention Journal Watch Cardiology, December 30, 2005; 2005(1230): 11 - 11. [Full Text]
|
|
|
|
|
|
J A Wedzicha and T A R Seemungal Inhaled corticosteroids in COPD: a light at the end of the tunnel? Thorax, December 1, 2005; 60(12): 977 - 978. [Full Text] [PDF]
|
|
|
|
|
|
G. J. Bombassei The Effects of a Smoking Cessation Intervention on 14.5-Year Mortality Ann Intern Med, October 18, 2005; 143(8): 615 - 615. [Full Text] [PDF]
|
|
|
|
|
|
M. C. Mathew The Effects of a Smoking Cessation Intervention on 14.5-Year Mortality Ann Intern Med, October 18, 2005; 143(8): 614 - 615. [Full Text] [PDF]
|
|
|
|
 |
|
 J. B Schorling A smoking cessation programme plus inhaled ipratropium improved survival in asymptomatic airway obstruction Evid. Based Med., October 1, 2005; 10(5): 143 - 143. [Full Text] [PDF]
|
|
|
|
 |
|
 Y. E. Miller Pathogenesis of Lung Cancer: 100 Year Report Am. J. Respir. Cell Mol. Biol., September 1, 2005; 33(3): 216 - 223. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. Anthonisen and R. Murray A new childhood pathway for transmission of an increased likelihood of smoking? Can. Med. Assoc. J., August 16, 2005; 173(4): 382 - 383. [Full Text] [PDF]
|
|
|
|
|
|
Long-Term Survival After a Smoking-Cessation Intervention Journal Watch Cardiology, March 25, 2005; 2005(325): 8 - 8. [Full Text]
|
|
|
|
 |
|
 Smoking Cessation Intervention Lowers Mortality Rate Journal Watch (General), February 22, 2005; 2005(222): 6 - 6. [Full Text]
|
|
|
|
|
|
J. M. Samet Smoking Kills: Experimental Proof from the Lung Health Study Ann Intern Med, February 15, 2005; 142(4): 299 - 301. [Full Text] [PDF]
|
|
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