Multi-Organ Failure and Sepsis Collection
 1-16 of 16 Articles
ACP Journal Club |  18 August 2015
In early septic shock, early goal-directed therapy did not reduce 90-day mortality
Dharmvir S. Jaswal, MD; Peter Q. Eichacker, MD
Ann Intern Med. 2015;163(4):JC10. doi:10.7326/ACPJC-2015-163-4-010
ACP Journal Club |  17 March 2015
Early goal-directed therapy did not reduce mortality more than usual care in early septic shock
Andrew Muck, MD; Bruce D. Adams, MD
Ann Intern Med. 2015;162(6):JC4. doi:10.7326/ACPJC-2015-162-6-004
ACP Journal Club |  18 November 2014
Review: In sepsis, the effect of resuscitation with crystalloid and colloid fluids on mortality varies
Sameer S. Kadri, MD; Robert L. Danner, MD
Ann Intern Med. 2014;161(10):JC12. doi:10.7326/0003-4819-161-10-201411180-02012
ACP Journal Club |  15 July 2014
In patients with severe sepsis, adding albumin to crystalloid solution did not reduce 28- or 90-day mortality
B. Taylor Thompson, MD
Ann Intern Med. 2014;161(2):JC6. doi:10.7326/0003-4819-161-2-201407150-02006
ACP Journal Club |  15 July 2014
In septic shock, MAP targets of 80 to 85 mm Hg vs 65 to 70 mm Hg did not differ for 28-day mortality
B. Taylor Thompson, MD
Ann Intern Med. 2014;161(2):JC7. doi:10.7326/0003-4819-161-2-201407150-02007
ACP Journal Club |  17 June 2014
In septic shock, early goal-directed or standard protocol-based therapy did not reduce mortality
Kevin M. King, FACEP, MD; Bruce D. Adams, FACEP, MD
Ann Intern Med. 2014;160(12):JC9. doi:10.7326/0003-4819-160-12-201406170-02009
ACP Journal Club |  19 February 2013
Review: Etomidate increased mortality and adrenal insufficiency in adults with sepsis
Ronald G. Pearl, MD
Ann Intern Med. 2013;158(4):JC2-10. doi:10.7326/0003-4819-158-4-201302190-02010
ACP Journal Club |  16 October 2012
Hydroxyethyl starch 130/0.42 increased death at 90 days compared with Ringer's acetate in severe sepsis
Jason M. Elinoff, MD; Robert L. Danner, MD
Ann Intern Med. 2012;157(8):JC4-6. doi:10.7326/0003-4819-157-8-201210160-02006
ACP Journal Club |  21 August 2012
Drotrecogin alfa (activated) did not reduce mortality at 28 or 90 days in patients with septic shock
Christian Brun-Buisson, MD
Ann Intern Med. 2012;157(4):JC2-11. doi:10.7326/0003-4819-157-4-201208210-02011
ACP Journal Club |  20 July 2010
Review: Enteral nutrition reduces mortality, multiple organ failure, and systemic infection more than TPN in acute pancreatitis
Shahnaz Sultan, MD, MHSc; Chris E. Forsmark, MD
Ann Intern Med. 2010;153(2):JC1-6. doi:10.7326/0003-4819-153-2-201007200-02006
ACP Journal Club |  18 May 2010
Intensive insulin therapy did not reduce mortality more than conventional therapy in septic shock treated with corticosteroids
Katherine J. Deans, MD; Peter C. Minneci, MD
Ann Intern Med. 2010;152(10):JC5-5. doi:10.7326/0003-4819-152-10-201005180-02005
ACP Journal Club |  19 May 2009
Review: Pneumococcal vaccination is not effective for preventing pneumonia, bacteremia, bronchitis, or mortality
Jennie Johnstone, MD
Ann Intern Med. 2009;150(10):JC5-4. doi:10.7326/0003-4819-150-10-200905190-02004
ACP Journal Club |  20 January 2009
Review: Tight glucose control reduces septicemia, but not death, and increases hypoglycemia in critically ill adults
Peter Dodek, MD
Ann Intern Med. 2009;150(2):JC1-5. doi:10.7326/0003-4819-150-2-200901200-02005
ACP Journal Club |  16 September 2008
Low-dose vasopressin did not reduce mortality more than norepinephrine in septic shock
Dennis G. Maki, MD, MACP
Ann Intern Med. 2008;149(6):JC3-14. doi:10.7326/0003-4819-149-6-200809160-02014
ACP Journal Club |  17 June 2008
Intensive insulin therapy and starch (HES 200/0.5) had some risk and no clear benefit in severe sepsis
Deborah Cook, MD; Lauralyn McIntyre, MD
Ann Intern Med. 2008;148(12):JC4-4. doi:10.7326/0003-4819-148-12-200806170-02004
ACP Journal Club |  17 June 2008
Low-dose hydrocortisone did not improve survival in patients with septic shock but reversed shock earlier
Francois Lamontagne, MD, MSc; Maureen O. Meade, MD, MSc
Ann Intern Med. 2008;148(12):JC4-6. doi:10.7326/0003-4819-148-12-200806170-02006
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