Table of Contents

January 6, 2004; 140 (1)

Articles

  • Coffee Consumption and Risk for Type 2 Diabetes Mellitus

    • Eduardo Salazar-Martinez,
    • Walter C. Willett,
    • Alberto Ascherio,
    • JoAnn E. Manson,
    • Michael F. Leitzmann,
    • Meir J. Stampfer,
    • and Frank B. Hu
    Ann Intern Med January 6, 2004 140:1-8

    The authors found that higher coffee consumption was associated with a lower incidence of type 2 diabetes mellitus, even after adjustment for age, body mass index, and other risk factors. Caffeine intake from all sources appears to be the determining factor in this relationship.

  • The Prevalence of Nontraditional Risk Factors for Coronary Heart Disease in Patients with Chronic Kidney Disease

    • Paul Muntner,
    • L. Lee Hamm,
    • John W. Kusek,
    • Jing Chen,
    • Paul K. Whelton,
    • and Jiang He
    Ann Intern Med January 6, 2004 140:9-17

    In this cross-sectional study based on the Third National Health and Nutrition Examination Survey, patients with chronic kidney disease had lower levels of apolipoprotein A1 and higher levels of homocysteine, lipoprotein(a), fibrinogen, and C-reactive protein.

  • Differential Time to Positivity: A Useful Method for Diagnosing Catheter-Related Bloodstream Infections

    • Issam Raad,
    • Hend A. Hanna,
    • Badie Alakech,
    • Ioannis Chatzinikolaou,
    • Marcella M. Johnson,
    • and Jeffrey Tarrand
    Ann Intern Med January 6, 2004 140:18-25

    The authors drew blood cultures simultaneously from the catheter and a peripheral vein. When cultures from the catheter turned positive at least 120 minutes sooner than cultures from a peripheral vein (“differential time to positivity”), the odds that the bacteremia was catheter-related increased substantially.

  • International Prospective Study of Klebsiella pneumoniae Bacteremia: Implications of Extended-Spectrum β-Lactamase Production in Nosocomial Infections

    • David L. Paterson,
    • Wen-Chien Ko,
    • Anne Von Gottberg,
    • Sunita Mohapatra,
    • Jose Maria Casellas,
    • Herman Goossens,
    • Lutfiye Mulazimoglu,
    • Gordon Trenholme,
    • Keith P. Klugman,
    • Robert A. Bonomo,
    • Louis B. Rice,
    • Marilyn M. Wagener,
    • Joseph G. McCormack,
    • and Victor L. Yu
    Ann Intern Med January 6, 2004 140:26-32

    Production of extended-spectrum β-lactamases by Klebsiella pneumoniae is a widespread nosocomial problem. Appropriate infection control and antibiotic management strategies are needed to stem the spread of this emerging form of antibiotic resistance.

Improving Patient Care

  • Patient Safety Is Not Enough: Targeting Quality Improvements To Optimize the Health of the Population

    • Steven H. Woolf
    Ann Intern Med January 6, 2004 140:33-36

    Ensuring patient safety is essential for better health care, but preoccupation with patient safety could distract us from other problems that pose a greater threat to health.

Review

  • Following the Molecular Pathways toward an Understanding of the Pathogenesis of Systemic Sclerosis

    • Sergio A. Jimenez and
    • Chris T. Derk
    Ann Intern Med January 6, 2004 140:37-50

    This review discusses the clinical and physiologic principles of systemic sclerosis, a disease of unknown origin characterized by excessive deposition of collagen and other connective tissue macromolecules in skin and many internal organs, prominent changes in the microvasculature, and humoral and cellular immunologic abnormalities.

Perspectives

  • Malpractice Reform Must Include Steps To Prevent Medical Injury

    • Stephen C. Schoenbaum and
    • Randall R. Bovbjerg
    Ann Intern Med January 6, 2004 140:51-53

    In the current malpractice insurance crisis, physicians have focused their advocacy and energy primarily on rapidly increasing liability premiums and demands for legal reform, especially caps on damages. An even more important focus, however, is prevention of injury and improvement of patient safety.

  • A Typology of Shared Decision Making, Informed Consent, and Simple Consent

    • Simon N. Whitney,
    • Amy L. McGuire,
    • and Laurence B. McCullough
    Ann Intern Med January 6, 2004 140:54-59

    Informed consent is the legal process used to advance patient autonomy in health care. Shared decision making is a widely promoted ethical approach to the same problem. We should think of these 2 processes as distinct, clinically and ethically, as we approach medical decisions.

Editorials

  • Beyond (or Back to) Traditional Risk Factors: Preventing Cardiovascular Disease in Patients with Chronic Kidney Disease

    • Lawrence J. Appel
    Ann Intern Med January 6, 2004 140:60-61

    In this issue, Muntner and colleagues show that persons with chronic kidney disease have a high prevalence of nontraditional risk factors for cardiovascular disease (CVD). The importance of these risk factors is uncertain in the general population and in patients with chronic kidney disease. Whether they cause CVD or are merely markers of CVD risk is unclear from the available evidence.

  • Catheters, Microbes, Time, and Gold Standards

    • Barry M. Farr
    Ann Intern Med January 6, 2004 140:62-64

    The study by Raad and colleagues in this issue suggests that a shorter time to positivity in blood cultures drawn from a vascular catheter is a useful diagnostic approach for catheter-related bloodstream infection. Raad and colleagues also note that the specificity (but not the sensitivity) of this test was lower in patients already taking antibiotics when blood cultures were drawn.

Letters

  • Risk Stratification for Noncardiac Surgery

    • Shaun D. Frost and
    • Franklin A. Michota
    Ann Intern Med January 6, 2004 140:W-1

  • Risk Stratification for Noncardiac Surgery

    • Steven L. Cohn
    Ann Intern Med January 6, 2004 140:W-2

  • Risk Stratification for Noncardiac Surgery

    • Paul A. Grayburn and
    • L. David Hillis
    Ann Intern Med January 6, 2004 140:W-3

  • Smallpox Vaccination Risks and Public Policy

    • Brian W. Cooper
    Ann Intern Med January 6, 2004 140:67

  • Smallpox Vaccination Risks and Public Policy

    • J. Michael Lane and
    • Joel Goldstein
    Ann Intern Med January 6, 2004 140:67

  • Complementary and Alternative Medical Education

    • Samuel Neff
    Ann Intern Med January 6, 2004 140:67

  • Complementary and Alternative Medical Education

    • Peter Manu
    Ann Intern Med January 6, 2004 140:67-68

  • Complementary and Alternative Medical Education

    • Edzard Ernst
    Ann Intern Med January 6, 2004 140:68

  • Complementary and Alternative Medical Education

    • Mary P. Guerrera
    Ann Intern Med January 6, 2004 140:68

  • Complementary and Alternative Medical Education

    • Miriam S. Wetzel,
    • Ted J. Kaptchuk,
    • David M. Eisenberg,
    • and Aviad Haramati
    Ann Intern Med January 6, 2004 140:68-69

  • The Future of Primary Care

    • Clifton R. Cleaveland
    Ann Intern Med January 6, 2004 140:69

  • The Future of Primary Care

    • Clair Morud
    Ann Intern Med January 6, 2004 140:69

  • The Future of Primary Care

    • Scott A. Shipman,
    • Jon D. Lurie,
    • and David C. Goodman
    Ann Intern Med January 6, 2004 140:69

  • Payment and the Future of Primary Care

    • Robert A. Murden
    Ann Intern Med January 6, 2004 140:70

  • Hospice Benefits and Phase I Cancer Trials

    • Robert Avery
    Ann Intern Med January 6, 2004 140:70

  • Hospice Benefits and Phase I Cancer Trials

    • Donald L. Trump
    Ann Intern Med January 6, 2004 140:70-71

  • Hospice Benefits and Phase I Cancer Trials

    • Ira Byock and
    • Steven H. Miles
    Ann Intern Med January 6, 2004 140:71

  • Alzheimer Disease: Current Concepts and Emerging Diagnostic and Therapeutic Strategies

    • Thomas E. Finucane
    Ann Intern Med January 6, 2004 140:71

  • Diagnostic Evaluation of Elderly Patients with Mild Memory Problems

    • Ronald Hirsch
    Ann Intern Med January 6, 2004 140:71

  • Diagnostic Evaluation of Elderly Patients with Mild Memory Problems

    • Monica S. Horton and
    • Jason E. Schillerstrom
    Ann Intern Med January 6, 2004 140:71-72

  • Diagnostic Evaluation of Elderly Patients with Mild Memory Problems

    • Jason Karlawish and
    • Christopher M. Clark
    Ann Intern Med January 6, 2004 140:72

  • Optimized Virologic Response in Hepatitis C Virus Genotype 4 with Peginterferon-α2a and Ribavirin

    • Moises Diago,
    • Tarek Hassanein,
    • Juan Rodés,
    • Andrew M. Ackrill,
    • and Farhad Sedarati
    Ann Intern Med January 6, 2004 140:72-73

  • Gatifloxacin-Induced Hepatotoxicity and Acute Pancreatitis

    • Onki Cheung,
    • Kapil Chopra,
    • Tina Yu,
    • Michael A. Nalesnik,
    • Shirish Amin,
    • and A. Obaid Shakil
    Ann Intern Med January 6, 2004 140:73-74

  • Arm Position and Blood Pressure Measurement

    • Thomas J. Hemingway,
    • David A. Guss,
    • and Diego Abdelnur
    Ann Intern Med January 6, 2004 140:74-75

Medical Writings: Book Notes

  • The Vaccine Handbook: A Practical Guide for Clinicians

    • Lisa A. Jackson and
    • Kathleen M. Neuzil
    Ann Intern Med January 6, 2004 140:76

  • Violence against Women: A Physician's Guide to Identification and Management

    • Patricia R. Salber
    Ann Intern Med January 6, 2004 140:76

Ad Libitum

Book Listings

  • Book Listings

    Ann Intern Med January 6, 2004 140:0

Medical Notices

  • Medical Notices

    Ann Intern Med January 6, 2004 140:0

Summaries for Patients

  • Coffee Drinkers at Lower Risk for Type 2 Diabetes

    Ann Intern Med January 6, 2004 140:I-17

  • Associations of Newer Cardiac Risk Factors with Chronic Kidney Disease

    Ann Intern Med January 6, 2004 140:I-26

  • Diagnosing Catheter-Related Bloodstream Infections

    Ann Intern Med January 6, 2004 140:I-39

  • Worldwide Prevalence of Antibiotic Resistance in the Bacteria Klebsiella pneumoniae

    Ann Intern Med January 6, 2004 140:I-43
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This Issue

January 6, 2004; 140 (1)
  1. Articles
  2. Improving Patient Care
  3. Review
  4. Perspectives
  5. Editorials
  6. Letters
  7. Medical Writings: Book Notes
  8. Ad Libitum
  9. Book Listings
  10. Medical Notices
  11. Summaries for Patients

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