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IN THIS ISSUE
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European data suggest that Fusobacterium necrophorum causes at least 10% of cases of pharyngitis. In this cross-sectional study, the authors sought to estimate the prevalence of F. necrophorum, Mycoplasma pneumoniae, and group A or C/G β-hemolytic streptococcal pharyngitis in a university student health clinic.
This study randomly assigned adults with the metabolic syndrome to either a simple high-fiber diet or a more complex diet based on the multicomponent American Heart Association dietary guidelines. Although participants assigned to the multicomponent advice lost slightly more weight, participants in both groups lost weight, suggesting that simple dietary advice might be a reasonable option for those unable or unwilling to follow more complex dietary advice.
Data to inform appropriate blood pressure (BP) targets for patients with chronic kidney disease (CKD) are incomplete. This study found that analyses using time-updated BP with adjustment for updated covariates showed stronger associations between elevated systolic BP and the progression of CKD than analyses based on baseline systolic BP.
Accurate risk prediction is a vital component in the primary prevention of atherosclerotic cardiovascular disease. This study evaluated the performance of 4 commonly used risk prediction tools and found that all either over- or underestimated risk and performed differently in men and women.
Prescriptions of opioid medications for chronic pain have increased dramatically, as have opioid overdoses, abuse, and other harms and uncertainty about long-term effectiveness. This review found scant and insufficient evidence that long-term opioid therapy for chronic pain improves function, quality of life, or pain outcomes.
The authors provide a step-by-step tutorial for selecting data collection tools; constructing forms; and abstracting, managing, and archiving data for systematic reviews.
This abridged report from a National Institutes of Health workshop addresses the role of opioids in the treatment of chronic pain. It identifies several key evidence gaps and research priorities.
In this position paper, the Medical Informatics Committee of the American College of Physicians reviews the current and emerging purposes of clinical documentation, the drivers that may influence or distract from these purposes, and the opportunities and challenges that have arisen from electronic health records.
In this commentary, the authors discuss ethical issues in the provision of life-sustaining therapies, such as cardiopulmonary resuscitation and dialysis, to patients with Ebola being cared for in developed countries.
This commentary discusses the benefits and risks of data sharing from the perspective of persons with experience in academic medicine, government, and medical publishing, as well as the pharmaceutical industry.
This commentary discusses the Institute of Medicine report on sharing clinical trial data and envisions a world with realigned incentives so that the maximum benefits can be derived from making more clinical trial data available.
The Framingham Study is the topic of this issues discussion from the Annals archives.
In this issue, Centor and colleagues estimate the prevalence of F. necrophorum, M. pneumoniae, and group A or C/G β-hemolytic streptococcal pharyngitis in a university student health clinic. The editorialist cautions clinicians to be aware of the various organisms that cause pharyngitis but not to overcomplicate management.
In this issue, DeFilippis and colleagues examined several prominent risk prediction tools for cardiovascular disease in which they found cases of overestimation and underestimation. The editorialists believe that the study serves as a crucial test of external validation and demands the attention of both clinicians and policymakers.
In this issue, the Medical Informatics Committee of the American College of Physicians reviews the current and emerging purposes of clinical documentation. The editorialist urges providers and other stakeholders to view such documentation as a fundamental tool for improving patient care.
The Consult Guys bring a new perspective to the art and science of medicine with lively discussion and analysis of real-world cases and situations.