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This modeling study, conducted to inform new recommendations from the U.S. Preventive Services Task Force, evaluates the balance of benefits and harms of routine aspirin use for men and women in different age and cardiovascular risk groups.

Topics: aspirin, cardiovascular diseases, colorectal cancer, decision analysis
  
Kevin A. Brown, PhD; Makoto Jones, MD; Nick Daneman, MD; Frederick R. Adler, PhD; Vanessa Stevens, PhD; Kevin E. Nechodom, BSc; Matthew B. Goetz, MD; Matthew H. Samore, MD; and Jeanmarie Mayer, MD
Includes: Audio/Video

This multilevel case–control study about Clostridium difficile incidence in 86 health care regions of the Veteran Health Administration examined how individual and regional factors affect infection risk, including antibiotic use and the importation of cases of acute care C difficile infection to long-term care facilities.

Topics: antibiotics, clostridium difficile infection, internship and residency, long-term care, acute care, medical ...
  

Little is known about the effect of the Medicaid expansions on health care utilization, access to care, and health among persons gaining coverage. The results of this quasi-experimental study suggest that Medicaid expansion seems to be achieving the broad goals of the Patient Protection and Affordable Care Act.

Topics: medicaid, patient protection and affordable care act, non-randomized controlled trials
  
Janelle M. Guirguis-Blake, MD; Corinne V. Evans, MPP; Caitlyn A. Senger, MPH; Elizabeth A. O'Connor, PhD; and Evelyn P. Whitlock, MD, MPH

This systematic review for the U.S. Preventive Services Task Force examines evidence about the benefits of aspirin for the primary prevention of cardiovascular events in adults aged 40 years or older and modification of effects by age, sex, and diabetes.

Topics: aspirin, cardiovascular diseases
  
Jessica Chubak, PhD, MBHL; Evelyn P. Whitlock, MD, MPH; Selvi B. Williams, MD, MPH; Aruna Kamineni, PhD, MPH; Brittany U. Burda, MPH; Diana S.M. Buist, PhD, MPH; and Melissa L. Anderson, MS

This systematic review for the U.S. Preventive Services Task Force reports effects of aspirin on total cancer mortality and incidence in adults eligible for cardiovascular primary prevention and on colorectal cancer mortality and incidence in adults at average risk.

Topics: aspirin, cancer, mortality, cardiovascular diseases
  
Evelyn P. Whitlock, MD, MPH; Brittany U. Burda, MPH; Selvi B. Williams, MD, MPH; Janelle M. Guirguis-Blake, MD; and Corinne V. Evans, MPP

This systematic review for the U.S. Preventive Services Task Force describes the risk for serious bleeding in adults regularly using aspirin to prevent cardiovascular disease.

Topics: aspirin, hemorrhage, primary prevention, cardiovascular diseases
  

This guideline from the U.S. Preventive Services Task Force addresses aspirin use for the prevention of cardiovascular disease and colorectal cancer. The recommendations apply to adults aged 40 years or older without known cardiovascular disease and without increased bleeding risk.

Topics: aspirin, cardiovascular diseases
  

The editorialist discusses the updated U.S. Preventive Services Task Force recommendation statement on aspirin for the primary prevention of cardiovascular disease and reflects on future research avenues that would create a strong evidence base for public policy.

Topics: aspirin, public policy, disease prevention
  

Wherry and Miller's quasi-experimental analysis of National Health Interview Survey data examined changes between 2010 to 2013 and late 2014 in key patient-centered outcomes among low-income adults in states that did and did not expand Medicaid in 2014. The editorialist discusses the insight these data provide about the early effects of Medicaid expansions.

Topics: medicaid
  
Vivek Kumar, BS; Jason Kessler, MD, MPH; and Elisabeth J. Cohen, MD
Topics: #
  
Phuc Le, PhD, MPH; and Michael B. Rothberg, MD, MPH
Topics: #
  
Vincent Mallet, MD, PhD; Rebecca Sberro-Soussan; Anais Vallet-Pichard, MD; Anne-Marie Roque-Afonso, MD, PhD; and Stanislas Pol, MD, PhD
Topics: #
  
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Topics: diabetes mellitus, diabetes mellitus, type 2, antihypertensive agents
  
Topics: activities of daily living, hospitals, inpatient, transition of care, geriatric assessment, follow-up ...
  
Topics: vision, elderly, visual impairment
  
Topics: risk assessment, genetics, diet
  
Topics: atrial fibrillation, cardiovascular event, symptom onset
  
Topics: cardiac arrhythmia, fluoroquinolones
  
Topics: macrolides, ventricular arrhythmia, elderly
  
Topics: atrial fibrillation, ischemic stroke, cerebrovascular accident
  
Topics: angina pectoris, mortality, proximal isovelocity surface area
  
Topics: systemic lupus erythematosus, framingham risk calculator
  

The Consult Guys bring a new perspective to the art and science of medicine with lively discussion and analysis of real-world cases and situations.

Topics: consultation, hematuria
  
Topics: aspirin, cardiovascular disease risk factors
  
Topics: aspirin, colorectal cancer, primary prevention of cardiovascular disease
  
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