Annals of Internal Medicine

Table of Contents

15 April 1996, Vol. 124. No. 8

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Articles

The Effectiveness of Early Treatment with “Second-Line” Antirheumatic Drugs: A Randomized, Controlled Trial

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Agnes van der Heide, MD; Johannes W.G. Jacobs, MD; Johannes W.J. Bijlsma, MD; Anton H.M. Heurkens, MD; Christina van Booma-Frankfort, MD; Maaike J. van der Veen, MD; Huub C.M. Haanen, MD; and Dick M. Hofman, MD

Topics: rheumatoid arthritis, glucocorticoids, anti-inflammatory agents, non-steroidal, antirheumatic agents, surrogate endpoints

Ann Intern Med. 1996;124(8):699-707. doi:10.7326/0003-4819-124-8-199604150-00001

Growth Hormone Replacement in Healthy Older Men Improves Body Composition but Not Functional Ability

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Maxine A. Papadakis, MD; Deborah Grady, MD, MPH; Dennis Black, PhD; Mary Jo Tierney, RN, MS; Gretchen A.W. Gooding, MD; Morris Schambelan, MD; and Carl Grunfeld, MD, PhD

Topics: somatotropin, activities of daily living, body composition, somatropin, elderly

Ann Intern Med. 1996;124(8):708-716. doi:10.7326/0003-4819-124-8-199604150-00002

Once-Daily Aminoglycoside Dosing in Immunocompetent Adults: A Meta-Analysis

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Rosemarie Hatala, MD, MSc; Tuan Dinh, MSc, RPh; and Deborah J. Cook, MD, MSc

Topics: aminoglycosides, toxic effect, nephrotoxicity

Ann Intern Med. 1996;124(8):717-725. doi:10.7326/0003-4819-124-8-199604150-00003

Pennyroyal Toxicity: Measurement of Toxic Metabolite Levels in Two Cases and Review of the Literature

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Ilene B. Anderson, PharmD; Walter H. Mullen, PharmD; James E. Meeker, PhD; Siamak C. Khojasteh-Bakht, MS; Shimako Oishi, PhD; Sidney D. Nelson, PhD; and Paul D. Blanc, MD

Topics: toxic effect, ingestion, pennyroyal, metabolites

Ann Intern Med. 1996;124(8):726-734. doi:10.7326/0003-4819-124-8-199604150-00004

Brief Communications

Colonic Bacillary Angiomatosis

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Young B. Huh, MD; Suzanne Rose, MD; Robert E. Schoen, MD, MPH; Susan Hunt, MD; David C. Whitcomb, MD, PhD; and Sydney Finkelstein, MD

Topics: bacillary angiomatosis, colon

Ann Intern Med. 1996;124(8):735-737. doi:10.7326/0003-4819-124-8-199604150-00005

Detection of a Clonal BCL2 Gene Rearrangement in Tissues from a Patient with Whipple Disease

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Thierry Fest, MD; Benedicte Pron, MD; Marie-Paule Lefranc, PhD; Catherine Pierre, MD; Regis Angonin, MD; Benoit de Wazieres, MD; Zohra Soua, MD; and Jean-Louis Dupond, MD

Topics: polymerase chain reaction, whipple disease, southern blot assay, bcl2 gene

Ann Intern Med. 1996;124(8):738-740. doi:10.7326/0003-4819-124-8-199604150-00006

Reviews

Reported Complications of Silicone Gel Breast Implants: An Epidemiologic Review

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Barbara G. Silverman, MD, MPH; S. Lori Brown, PhD, MPH; Roselie A. Bright, ScD; Ronald G. Kaczmarek, MD, MPH; Janet B. Arrowsmith-Lowe, MD; and David A. Kessler, MD

Topics: connective tissue disease, contracture, silicone gels, silicones, breast implants, women, breast cancer, ...

Ann Intern Med. 1996;124(8):744-756. doi:10.7326/0003-4819-124-8-199604150-00008

Academia and the Profession

Checklist of Information for Inclusion in Reports of Clinical Trials

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The Asilomar Working Group on Recommendations for Reporting of Clinical Trials in the Biomedical Literature*

Topics: brain tumor, cancer, biometry, cancer care facilities, crataegus, florida, greenland, internal medicine, ...

Ann Intern Med. 1996;124(8):741-743. doi:10.7326/0003-4819-124-8-199604150-00007

Ideas and Opinions

Noncardiac Surgery in the Cardiac Patient: What Is the Question?

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Monty M. Bodenheimer, MD

Topics: myocardial infarction, coronary arteriosclerosis, cardiac event, heart

Ann Intern Med. 1996;124(8):763-766. doi:10.7326/0003-4819-124-8-199604150-00010

Screening for Cardiac Disease in Patients Having Noncardiac Surgery

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Lee A. Fleisher, MD; and Kim A. Eagle, MD

Topics: coronary revascularization, heart diseases, congestive heart failure, thallium, vascular surgical procedures, diagnostic ...

Ann Intern Med. 1996;124(8):767-772. doi:10.7326/0003-4819-124-8-199604150-00011

Abroad

Plasma Cytokines, Cytokine Antagonists, and Disease Progression in African Women Infected with HIV-1

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Donald M. Thea, MD; Reuven Porat, MD; Khondi Nagimbi, MD; Matela Baangi, MD; Michael E. St. Louis, MD; Gilla Kaplan, PhD; Charles A. Dinarello, MD; and Gerald T. Keusch, MD

Topics: cytokine, acquired immunodeficiency syndrome, interleukin-1, disease progression, hiv-1, plasma, women, antagonists

Ann Intern Med. 1996;124(8):757-762. doi:10.7326/0003-4819-124-8-199604150-00009

Editorials

Rheumatoid Arthritis: Treat Now, Not Later!