0

Want to Subscribe?

Learn more about subscription options

Basic View  |  Expanded View

For histologically mild chronic hepatitis C, initial combination therapy compared with periodic liver biopsy should reduce the future risk for cirrhosis, prolong life, and be cost-effective.

Topics: biopsy, hepatitis c, chronic, liver cirrhosis, watchful waiting, liver biopsy, cost-effectiveness analysis, ...
  
John N. Galgiani, MD; Antonino Catanzaro, MD; Gretchen A. Cloud, MS; Royce H. Johnson, MD; Paul L. Williams, MD; Laurence F. Mirels, MD; Faris Nassar, MD; Jon E. Lutz, MD; David A. Stevens, MD; P. Kay Sharkey, MD; Vipul R. Singh, MD; Robert A. Larsen, MD; Kathy L. Delgado, LPN; Cynthia Flanigan, BS; and Michael G. Rinaldi, PhD

Neither fluconazole nor itraconazole showed statistically superior efficacy in nonmeningeal coccidioidomycosis, although there was a trend toward slightly greater efficacy with itraconazole.

Topics: coccidioidomycosis, fluconazole, itraconazole, double-blind method, infection
  

A multicomponent program of warfarin management reduced the frequency of major bleeding in older patients. These findings support the premise that efforts to reduce the likelihood of major bleeding will lead to safe and effective use of warfarin therapy in older patients.

Topics: warfarin, hemorrhage, elderly
  
Ellen Marqusee, MD; Carol B. Benson, MD; Mary C. Frates, MD; Peter M. Doubilet, MD, PhD; P. Reed Larsen, MD, FRCP; Edmund S. Cibas, MD; and Susan J. Mandel, MD, MPH

Ultrasonography altered clinical management for 63% of patients referred to a thyroid nodule clinic after abnormal results on thyroid physical examination. The results suggest that routine thyroid ultrasonography should be seriously considered for all patients with suspected thyroid nodules.

Topics: ultrasonography, thyroid diseases, fine needle biopsy
  
Peter Schenk, MD; Christian Madl, MD; Shahrzad Rezaie-Majd, MD; Stephan Lehr; and Christian Müller, MD

Intravenous methylene blue improved hypoxemia and hyperdynamic circulation in patients with liver cirrhosis and severe hepatopulmonary syndrome.

Topics: hepatopulmonary syndrome, methylene blue, infusion procedures
  
Alexis M. Fenton, MD; Stephen C. Hammill, MD; Robert F. Rea, MD; Phillip A. Low, MD; and Win-Kuang Shen, MD

Vasovagal syncope is a common, difficult to manage clinical syndrome. Advancements are being made in laboratory investigations of its triggering mechanisms. Randomized, controlled trials of pharmacologic and nonpharmacologic interventions are needed.

Topics: vasovagal syncope, syncope
  
Conference Chair: David T. Felson, MD, MPH; Conference Organizer: Reva C. Lawrence, MPH; Discussants: Marc C. Hochberg, MD, MPH; Timothy McAlindon, MD, MPH; Paul A. Dieppe, MD; Marian A. Minor, PT, PhD; Steven N. Blair, PED; Brian M. Berman, MD; James F. Fries, MD; Morris Weinberger, PhD; Kate R. Lorig, RN, DrPH; Joshua J. Jacobs, MD; and Victor Goldberg, MD

Part 2 of this two-part conference focuses on treatments for osteoarthritis, including oral medications, alternative therapies, biomedical approaches, and surgery.

Topics: #
  

In this issue, Schenk and colleagues provide new insight into the pathogenesis of vasodilation in liver disease and raise extremely important therapeutic issues.

Topics: liver cirrhosis, methylene blue
  
Michael K. Williams, MD

Only by temporarily shedding our emotional armor for dying patients and their families will physicians be able to regain the trust of our individual patients and the trust of society as a whole.

Topics: #
  
Topics: #
  
Stephen S. Gottlieb, MD; Meenakshi Khatta, MS, CRNP; and Michael L. Fisher, MD
Topics: #
  
Dimitri Prybylski, PhD, MPH
Topics: #
  
Nancy A. Shadick, MD, MPH; Robert A. Lew, PhD; and Matthew H. Liang, MD, MPH
Topics: #
  
Buddha Basnyat; and R.M. Scott
Topics: #
  
Topics: #
  
Rebecca E. Rudolph, MD, MPH; Thomas L. Vaughan, MD, MPH; and Barry Storer, PhD
Topics: #
  
Dennis L. Desilvey, MD
Topics: #
  
Topics: #
  
Christina M. Puchalski, MD; David B. Larson, MD, MSPH; and Stephen G. Post, PhD
Topics: #
  
Rodney Syme, FRCS, FRACS
Topics: #
  
Topics: #
  
Rand A. David, MD
Topics: #
  
Mark W. Swaim, MD, PhD; Swati Agarwal, MD; and Wendell F. Rosse, MD
Topics: #
  
Kathleen A. Prendergast, MD; Carl L. Berg, MD; and Ralph Wisniewski, MD
Topics: #
  
David M. Hachey, PharmD; Michael P. O'Neil, MD; and Rex W. Force, PharmD, BCPS
Topics: #
  
Steven H. Yale, MD; and Joseph J. Mazza, MD
Topics: #
  
Topics: #
  
Topics: #
  

Naming is generally an act of tremendous symbolic and practical significance, and there is no reason to think it any less so in medical science. The growth of trial names in recent years reflects important professional and proprietary trends in medicine that deserve our attention.

Topics: #
  
Topics: #
  
Topics: #
  
Dennis J. Sullivan, MD
Topics: #
  
Dwaine Rieves, MD
Topics: #
  
Topics: hepatitis c, watchful waiting
  
Topics: coccidioidomycosis, fluconazole, itraconazole, infection
  
Topics: warfarin, hemorrhage, elderly
  
Topics: ultrasonography, thyroid nodule
  
Topics: hepatopulmonary syndrome, methylene blue
  
Topics: #
  
Karen E. Hauer, MD; and Neil Winawer, MD

This Update reviews key literature relevant to the care of hospitalized patients. Topics covered include pulmonary medicine, cardiology, infectious diseases, and end-of-life care.

Topics: #
  
Advertisement

Want to Subscribe?

Learn more about subscription options

Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.
(Required)
(Required)