Annals of Internal Medicine

Table of Contents

21 September 2010, Vol. 153. No. 6

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Articles

Sex-Based Outcomes of Darunavir–Ritonavir Therapy: A Single-Group Trial FREE

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Judith Currier, MD, MSc; Dawn Averitt Bridge, BIS; Debbie Hagins, MD; Carmen D. Zorrilla, MD; Judith Feinberg, MD; Robert Ryan, MSc; Ron Falcon, MD; Alan Tennenberg, MD, MPH; Joseph Mrus, MD, MSc; Kathleen Squires, MD, on behalf of the GRACE (Gender, Race, And Clinical Experience) Study Group

Topics: ritonavir, viral load result, women, anti-retroviral agents, darunavir, virologic failure, adverse event ...

Ann Intern Med. 2010;153(6):349-357. doi:10.7326/0003-4819-153-6-201009210-00002

Single-Dose Palifermin Prevents Severe Oral Mucositis During Multicycle Chemotherapy in Patients With Cancer: A Randomized Trial FREE

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Saroj Vadhan-Raj, MD; Jonathan Trent, MD; Shreyaskumar Patel, MD; Xiao Zhou, MD, PhD; Marcella M. Johnson, MS; Dejka Araujo, MD; Joseph A. Ludwig, MD; Shana O'Roark, RN, APN; Ann M. Gillenwater, MD; Carlos Bueso-Ramos, MD, PhD; Adel K. El-Naggar, MD, PhD; and Robert S. Benjamin, MD

Includes: Summaries For Patients

Topics: cancer, chemotherapy regimen, fgf7 protein, human, mucous inflammation, mucositis, oropharyngeal, single-dose regimen ...

Ann Intern Med. 2010;153(6):358-367. doi:10.7326/0003-4819-153-6-201009210-00003

Stool DNA Testing to Screen for Colorectal Cancer in the Medicare Population: A Cost-Effectiveness Analysis

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Iris Lansdorp-Vogelaar, PhD; Karen M. Kuntz, ScD; Amy B. Knudsen, PhD; Janneke A. Wilschut, MS; Ann G. Zauber, PhD; and Marjolein van Ballegooijen, MD, PhD

Topics: cancer, colorectal cancer, adenoma, medicare, fecal analysis, cost-effectiveness analysis, colorectal cancer screening, ...

Ann Intern Med. 2010;153(6):368-377. doi:10.7326/0003-4819-153-6-201009210-00004

Proton-Pump Inhibitors Are Associated With Increased Cardiovascular Risk Independent of Clopidogrel Use: A Nationwide Cohort Study FREE

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Mette Charlot, MD; Ole Ahlehoff, MD; Mette Lykke Norgaard, MD; Casper H. Jørgensen, MD; Rikke Sørensen, MD; Steen Z. Abildstrøm, MD, PhD; Peter Riis Hansen, MD, PhD, DMSc; Jan Kyst Madsen, MD, DMSc; Lars Køber, MD, DMSc; Christian Torp-Pedersen, MD, DMSc; and Gunnar Gislason, MD, PhD

Includes: Supplemental Content

Topics: myocardial infarction, clopidogrel, cardiovascular disease risk factors, proton pump inhibitors

Ann Intern Med. 2010;153(6):378-386. doi:10.7326/0003-4819-153-6-201009210-00005

Reviews

The Vulnerable Atherosclerotic Plaque: Scope of the Literature FREE

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Alawi A. Alsheikh-Ali, MD, MS; Georgios D. Kitsios, MD, PhD; Ethan M. Balk, MD, MPH; Joseph Lau, MD; and Stanley Ip, MD

Includes: Supplemental Content

Topics: atheroma, cardiovascular diseases, biological markers, diagnostic imaging, lipids, cardiovascular event, emotional vulnerability, ...

Ann Intern Med. 2010;153(6):387-395. doi:10.7326/0003-4819-153-6-201009210-00272

Clinical Guidelines

Screening for Testicular Cancer: An Evidence Review for the U.S. Preventive Services Task Force FREE

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Kenneth Lin, MD; and Ruta Sharangpani, MD, MPH

Topics: preventive medicine, advisory committees, testicular cancer, testicular malignant germ cell tumor

Ann Intern Med. 2010;153(6):396-399. doi:10.7326/0003-4819-153-6-201009210-00007

Academia and the Profession

Clinical Trials: Discerning Hype From Substance

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Thomas R. Fleming, PhD

Includes: Supplemental Content

Topics: fluorouracil, health services research, levamisole, idiopathic pulmonary fibrosis, women, interferon gamma-1b, medical ...

Ann Intern Med. 2010;153(6):400-406. doi:10.7326/0003-4819-153-6-201009210-00008

Ideas and Opinions

Health Care for Prisoners in Haiti FREE

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John P. May, MD; Patrice Joseph, MD; Jean William Pape, MD; and Ingrid A. Binswanger, MD, MPH

Topics: haiti, prisoners, correctional facilities

Ann Intern Med. 2010;153(6):407-410. doi:10.7326/0003-4819-153-6-201009210-00270

Editorials

Supportive Treatments for Oncology Patients: Not Just Icing on the Cake

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John F. Deeken, MD; and Louis M. Weiner, MD

Topics: academic medical centers, cancer care facilities, medical oncology, fgf7 protein, human, mucous ...

Ann Intern Med. 2010;153(6):411-412. doi:10.7326/0003-4819-153-6-201009210-00010

Conflicting Evidence: What's a Clinician to Do?

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Joao Paulo de Aquino Lima; and James M. Brophy, MD, PhD

Topics: myocardial infarction, clopidogrel, drug interactions, brazil, proton pump inhibitors, quebec, cardiovascular death ...

Ann Intern Med. 2010;153(6):413-415. doi:10.7326/0003-4819-153-6-201009210-00011

On Being a Patient

Survivor*

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Esther S. Tanzman, MD

Topics: #

Ann Intern Med. 2010;153(6):416-417. doi:10.7326/0003-4819-153-6-201009210-00012

Letters

Barriers to Herpes Zoster Vaccination

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Wim Opstelten, MD, PhD; Gerrit A. van Essen, MD, PhD; and Eelko Hak, MSc, PhD

Topics: #

Ann Intern Med. 2010;153(6):418. doi:10.7326/0003-4819-153-6-201009210-00014

Barriers to Herpes Zoster Vaccination

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Laura Hurley, MD, MPH; and Allison Kempe, MD, MPH

Topics: #

Ann Intern Med. 2010;153(6):418-419. doi:10.7326/0003-4819-153-6-201009210-00015

Important Differences in Measurement of Fetuin-A

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Edward R. Smith, MSc, PhD; and Stephen G. Holt, MBBS, PhD

Topics: #

Ann Intern Med. 2010;153(6):419. doi:10.7326/0003-4819-153-6-201009210-00016

Important Differences in Measurement of Fetuin-A

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Vincent M. Brandenburg, MD; Benjamin D. Parker, MD; and Joachim H. Ix, MD, MAS

Topics: #

Ann Intern Med. 2010;153(6):419-420. doi:10.7326/0003-4819-153-6-201009210-00017

Urine Drug Testing Is Still an Invaluable Resource for Primary Care

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Gary M. Reisfield, MD; Noni A. Graham, MPH; and Mark S. Gold, MD

Topics: #

Ann Intern Med. 2010;153(6):420. doi:10.7326/0003-4819-153-6-201009210-00018

Urine Drug Testing Is Still an Invaluable Resource for Primary Care

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Joanna L. Starrels, MD, MS; Daniel P. Alford, MD, MPH; and Barbara J. Turner, MD, MSEd, Executive Deputy Editor

Topics: #

Ann Intern Med. 2010;153(6):420-421. doi:10.7326/0003-4819-153-6-201009210-00019

Guidelines and Conflicts of Interest

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Zackary D. Berger, MD, PhD

Topics: #

Ann Intern Med. 2010;153(6):421. doi:10.7326/0003-4819-153-6-201009210-00020

Guidelines and Conflicts of Interest

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Giovanni A. Fava, MD

Topics: #

Ann Intern Med. 2010;153(6):421-422. doi:10.7326/0003-4819-153-6-201009210-00021

Guidelines and Conflicts of Interest

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Gordon Guyatt, MD, MSc; Holger Schünemann, MD, PhD; and Elie Akl, MD, PhD

Topics: #

Ann Intern Med. 2010;153(6):422. doi:10.7326/0003-4819-153-6-201009210-00022

A Rare Cause of Cardiac Ischemia: Systemic Lupus Erythematosus Presenting as the Hyperviscosity Syndrome

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Frank E. Corrigan III, MD; Andrew R. Leventhal, MD, PhD; Sabiha Khan, MD; Shaline Rao, MD; Lisa Christopher-Stine, MD, MPH; and Steven P. Schulman, MD

Topics: #

Ann Intern Med. 2010;153(6):422-424. doi:10.7326/0003-4819-153-6-201009210-00023

Ad Libitum

The Language of Grief

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Ronald Lands, MD

Topics: #

Ann Intern Med. 2010;153(6):417. doi:10.7326/0003-4819-153-6-201009210-00013

ACP Journal Club

Meta-analysis: Alteplase improves functional outcomes when given within 4.5 hours of stroke onset

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Topics: cerebrovascular accident, ischemic stroke, alteplase

Ann Intern Med. 2010;153(6):JC3-2. doi:10.7326/0003-4819-153-6-201009210-02002

A single, annual, high dose of oral vitamin D increased falls and fractures in older women

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Topics: fracture, vitamin d, elderly

Ann Intern Med. 2010;153(6):JC3-3. doi:10.7326/0003-4819-153-6-201009210-02003

Review: Statins do not reduce mortality in patients with no history of cardiovascular disease

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Topics: statins, cardiovascular diseases, mortality

Ann Intern Med. 2010;153(6):JC3-4. doi:10.7326/0003-4819-153-6-201009210-02004

Review: β-agonists increase asthma-related intubations and deaths in patients with asthma

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Topics: asthma, intubation, agonists

Ann Intern Med. 2010;153(6):JC3-5. doi:10.7326/0003-4819-153-6-201009210-02005

Review: Treatment for gestational diabetes reduces risk for shoulder dystocia

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Topics: gestational diabetes, shoulder dystocia

Ann Intern Med. 2010;153(6):JC3-6. doi:10.7326/0003-4819-153-6-201009210-02006

Review: Probiotics improve symptoms in adults with the irritable bowel syndrome

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Topics: probiotics, irritable bowel syndrome

Ann Intern Med. 2010;153(6):JC3-7. doi:10.7326/0003-4819-153-6-201009210-02007

Review: Direct thrombin inhibitors are similar to LMWH and vitamin K antagonists for preventing VTE after hip or knee replacement

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Topics: low-molecular-weight heparin, hip region, hip joint, knee replacement arthroplasty, vitamin k antagonist, ...

Ann Intern Med. 2010;153(6):JC3-8. doi:10.7326/0003-4819-153-6-201009210-02008

Review: Target-oriented drug treatment improves clinical outcomes more than routine care in rheumatoid arthritis

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Topics: pharmacotherapy, rheumatoid arthritis, treatment outcome

Ann Intern Med. 2010;153(6):JC3-9. doi:10.7326/0003-4819-153-6-201009210-02009

Review: Laparoscopic fundoplication is better than medical management for some quality-of-life measures in GERD

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Topics: gastroesophageal reflux disease, quality of life, laparoscopic fundoplication

Ann Intern Med. 2010;153(6):JC3-10. doi:10.7326/0003-4819-153-6-201009210-02010

Review: High-dose and non–high-dose proton pump inhibitors after endoscopic treatment do not differ for bleeding peptic ulcers

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Topics: peptic ulcer hemorrhage, proton pump inhibitors

Ann Intern Med. 2010;153(6):JC3-11. doi:10.7326/0003-4819-153-6-201009210-02011

Vitamin E, but not pioglitazone, improved nonalcoholic steatohepatitis in nondiabetic patients

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Topics: vitamin e, pioglitazone, steatohepatitis, non-alcoholic

Ann Intern Med. 2010;153(6):JC3-12. doi:10.7326/0003-4819-153-6-201009210-02012

Concomitant use of warfarin and cotrimoxazole or ciprofloxacin increased risk for admission for upper GI hemorrhage

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Topics: warfarin, ciprofloxacin, trimethoprim-sulfamethoxazole combination, upper gastrointestinal bleeding

Ann Intern Med. 2010;153(6):JC3-13. doi:10.7326/0003-4819-153-6-201009210-02013

Summaries for Patients

Palifermin Can Prevent Severe Oral Mucositis During Chemotherapy FREE

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Topics: chemotherapy regimen, fgf7 protein, human, mucositis, oropharyngeal

Ann Intern Med. 2010;153(6):I-44. doi:10.7326/0003-4819-153-6-201009210-00001

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