Mounting evidence is fueling excitement over the possibility of curing HIV infection. Research aimed at eliminating the need for continuous antiretroviral therapy includes approaches ranging from bone marrow transplantation, to aggressive early treatment of HIV infection, to withdrawal of antiretroviral therapy to permit the killing of HIV in biological reservoirs. This commentary discusses the complex ethical issues associated with such research.
Ann Intern Med. Published online 13 August 2013 doi:10.7326/0003-4819-159-7-201310010-00694