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Rethinking Randomized Clinical Trials for Comparative Effectiveness Research: The Need for Transformational Change
Bryan R. Luce, PhD, MBA; Judith M. Kramer, MD, MS; Steven N. Goodman, MD, MHS, PhD; Jason T. Connor, PhD; Sean Tunis, MD, MSc; Danielle Whicher, MHS; J. Sanford Schwartz, MD
Annals of Internal Medicine 2009;151:206-209. doi:10.7326/0003-4819-151-3-200908040-00126

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