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Single-Center Trials Show Larger Treatment Effects Than Multicenter Trials: Evidence From a Meta-epidemiologic Study

Agnes Dechartres, MD; Isabelle Boutron, MD, PhD; Ludovic Trinquart, MSc; Pierre Charles, MD; Philippe Ravaud, MD, PhD

Annals of Internal Medicine 2011;155:39-51. doi:10.7326/0003-4819-155-1-201107050-00006

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Annals of Internal Medicine

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