GILDO DEL NEGRO, M.D., M.P.H.; BERNARDO L. WAJCHENBERG, M.D.; VIRGILIO G. PEREIRA, M.D.; JOSÉ SHNAIDER, M.D.; A. B. DE ULHOA CINTRA, D.M., PH.D.; L. MARQUES DE ASSIS, M.D.; S. A. PRADO SAMPAIO, M.D.
The systemic mycotic diseases as etiologic agents of chronic adrenal insufficiency have been considered in the medical literature. Thus, histoplasmosis,1-5a cryptococcosis,2, 6 coccidioidomycosis,7, 8 and North American blastomycosis9-11 have been found to involve the adrenals. In some cases the clinical picture of Addison's disease has been produced.
South American blastomycosis is a systemic fungus disease, the visceral lesions of which frequently appear in the adrenals at autopsy. Extensive destruction of the adrenal glands has been reported, but no studies of adrenal function based on adrenocortical stimulation tests had been done ante-mortem. It is the purpose of this paper to report
DEL NEGRO G, WAJCHENBERG BL, PEREIRA VG, et al. ADDISON'S DISEASE ASSOCIATED WITH SOUTH AMERICAN BLASTOMYCOSIS12. Ann Intern Med. 1961;54:189–197. doi: 10.7326/0003-4819-54-2-189
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Published: Ann Intern Med. 1961;54(2):189-197.
Adrenal Disorders, Endocrine and Metabolism, Infectious Disease.
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