DOLORES MÉNDEZ-CASHION, M.D.; RICARDO CORDERO, M.D.
Congenital dermal sinuses are depressions or tracts lined with stratified squamous epithelium which apparently result from defective separation of the neuroectoderm from the epithelial ectoderm along the mid-dorsal aspect of the embryo. In 1926 Moise1 related these lesions to intracranial infection when he reported a case of staphylococcal meningitis in which the portal of entry was a congenital dermal sinus in the sacral region. His patient, an 18-year-old male, recovered after lumbar laminectomy with drainage. Several reports followed of meningitis secondary to similar lesions along the spinal axis.2-4
In 1949 Mount4 reported two cases of sinuses in the occipital area
MÉNDEZ-CASHION D, CORDERO R. RECURRENT MENINGITIS ASSOCIATED WITH CONGENITAL DERMAL SINUS1. Ann Intern Med. ;54:503–509. doi: 10.7326/0003-4819-54-3-503
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Published: Ann Intern Med. 1961;54(3):503-509.
CNS Infections, Infectious Disease, Neurology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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