ARNOLD L. WIDEN, M.D.; LEONARD CARDON, M.D., F.A.C.P.
The interesting observation has been made1-10 that salmonella osteomyelitis develops more frequently in patients with sickle-hemoglobinopathies than can be accounted for merely on the basis of chance occurrence.
Osteomyelitis is not a common complication of salmonella infections, since only 0.82% of cases of typhoid fever and 0.2% of paratyphoid infections develop skeletal involvement.11-15 Of 3,000 cases of salmonella infections (excluding Salmonella typhosa) bacteriologically identified by the New York Salmonella Center, only five cultures were obtained from cases of osteomyelitis—three due to Salmonella typhimurium, and one each due to Salmonella enteritidis and Salmonella panama.16, 17
In a review of salmonella osteomyelitis
WIDEN AL, CARDON L. SALMONELLA TYPHIMURIUM OSTEOMYELITIS WITH SICKLE CELL-HEMOGLOBIN C DISEASE: A REVIEW AND CASE REPORT1. Ann Intern Med. ;54:510–521. doi: 10.7326/0003-4819-54-3-510
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Published: Ann Intern Med. 1961;54(3):510-521.
Hematology/Oncology, Infectious Disease, Red Cell Disorders.
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