ALBERTO DAYSOG JR., M.D.; HAROLD L. DOBSON, M.D.; JAMES C. BRENNAN, M.D.
It has long been suspected that the vascular disease seen in patients with diabetes mellitus might not be directly related to the control, severity, or duration of the carbohydrate defect.1-8 If this is true, it modifies and broadens the etiologic concept of diabetes.
Of all forms of vascular disease, those found in the retina and in the kidney are the most specific for diabetes.9 The literature on the renal glomerular involvement in diabetes is difficult to interpret. The presence or absence of the nodular (Kimmelstiel-Wilson) lesion does not depend on the severity10 or on the clinical control7 of the carbohydrate
DAYSOG A, DOBSON HL, BRENNAN JC. RENAL GLOMERULAR AND VASCULAR LESIONS IN PREDIABETES AND IN DIABETES MELLITUS: A STUDY BASED ON RENAL BIOPSIES12. Ann Intern Med. 1961;54:672–684. doi: 10.7326/0003-4819-54-4-672
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Published: Ann Intern Med. 1961;54(4):672-684.
Cardiology, Coronary Risk Factors, Diabetes, Diabetic Nephropathy, Endocrine and Metabolism.
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