J. R. E.
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In this issue of the ANNALS appear four papers that illustrate the complementary roles of basic science and clinical medicine. One paper examines the effect of the antidiuretic hormone, vasopressin, on the mechanisms of solute and water transport in the bladder wall of the toad. A second reviews the elegant countercurrent exchanger and multiplier system that results from the special configurations and functions of nephrons and capillaries of the mammalian kidney; it is in this system that vasopressin facilitates the elaboration of a hypertonic urine. And the third and fourth present the clinical problem of the patient with polyuria and
E. JR. PREREQUISITE OF FREEDOM: A HYPERTONIC URINE. Ann Intern Med. ;54:827–831. doi: 10.7326/0003-4819-54-4-827
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Published: Ann Intern Med. 1961;54(4):827-831.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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