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Original Research |1 May 1961

THE CONCENTRATION OF ANTIHEMOPHILIC GLOBULIN (AHG) IN PATIENTS WITH CORONARY ARTERY DISEASE1

ARTHUR A. COOPERBERG, M.D.; JACOBO I. TEITELBAUM, M.D.

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Abstract

Blood coagulation bears an important relationship to atherosclerosis, first, because thrombosis is its most serious complication, and second, because one of the current theories of the pathogenesis of atherosclerosis is that the vascular lesions are initiated by mural thrombi. In both, a hypercoagulable state has been implicated as being responsible for the thrombosis.1, 2

Because of increasing understanding of the mechanism of blood coagulation, and newer technics, it is now possible to determine quantitatively the concentration of many clotting factors. It is felt that such factors, which are normally concerned with hemostasis, may be important in thrombus formation when present

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COOPERBERG AA, TEITELBAUM JI. THE CONCENTRATION OF ANTIHEMOPHILIC GLOBULIN (AHG) IN PATIENTS WITH CORONARY ARTERY DISEASE1. Ann Intern Med. 1961;54:899–907. doi: 10.7326/0003-4819-54-5-899

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Published: Ann Intern Med. 1961;54(5):899-907.

DOI: 10.7326/0003-4819-54-5-899

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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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