B. J. Kennedy, M.D., F.A.C.P.
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Adrenocortical hyperfunction has occurred in association with carcinomas not originating in the adrenal glands. These cancers included those from the bronchus, thymus, pancreas, and prostate. The syndrome has been characterized by an acute onset, occurrence in young adults, and a short duration of life. The fulminating course appears to be due to the adrenal cortical overactivity.
Three patients have been studied: (1) a 23-year-old female with a small-cell carcinoma of the thyroid with extensive metastases, bilateral pheochromecytoma, and hyperplasia of the adrenal cortex; (2) a 33-year-old male with Hodgkin's disease and adrenal hyperfunction; and (3) a 57-year-old male with metastatic
Kennedy BJ. Adrenocortical Hyperfunction in Cancer.. Ann Intern Med. 1961;54:1045. doi: https://doi.org/10.7326/0003-4819-54-5-1045_2
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Published: Ann Intern Med. 1961;54(5):1045.
Adrenal Disorders, Endocrine and Metabolism, Hematology/Oncology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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