J. W. Ferrebee, M.D.
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Transplants of bone marrow have been found to restore hematopoiesis in animals rendered aplastic by lethal exposure to radiation. Animals so restored have been found to accept transplants of other tissue from their marrow donors. Efforts to expand this information to the point of clinical usefulness in either the treatment of radiation casualty or the transplantation of whole organs have revealed certain problems. Clearly immunologic tolerance can be acquired. The difficulty has been to make the methods of its acquisition clinically acceptable. Investigation has revealed several methods of promise: the use of fetal rather than adult hematopoietic tissue to restore
Ferrebee JW. Organ and Bone Marrow Transplants.. Ann Intern Med. 1961;54:1051–1052. doi: https://doi.org/10.7326/0003-4819-54-5-1051_2
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Published: Ann Intern Med. 1961;54(5):1051-1052.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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