J. S. Chapman, M.D., (Assoc.)
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Sera of 33 patients with sarcoidosis or the benign hilar adenopathy syndrome have been studied by Ouchterlony double diffusion in agar. Antigens have consisted of defatted tuberculin-like material derived from type strains of anonymous Mycobacteria. These sera were obtained from several distinct geographic areas of the United States.
Twenty-eight of the 33 patients produced at least two bands against scotochromogenic antigens. Secondary reactions against photochromogenic and nonchromogenic antigens were found in a number of sera, but these reactions had a geographic variation corresponding to reported frequency of these organisms.
Three local patients when first seen possessed no detectable antibodies, but
Chapman JS. A Serological Reaction Associated with Sarcoidosis of Boeck.. Ann Intern Med. 1961;54:1062. doi: https://doi.org/10.7326/0003-4819-54-5-1062_1
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Published: Ann Intern Med. 1961;54(5):1062.
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