B. D. Cohen, M.D.; N. Spritz, M.D.; A. L. Rubin, M.D.; E. H. Luckey, M.D., F.A.C.P.
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Because of the occurrence of hypoglycemia in uremic patients during insulin and glucose treatment for hyperpotassemia a group of 20 patients with renal disease was studied with the standard insulin tolerance test. These were compared to 19 comparably ill patients free of renal disease. Although the initial hypoglycemia was identical a significantly delayed blood sugar was noted in the kidney disease group. These groups were re-examined using epinephrine and glucagon followed by periodic blood sugar determinations. The response to both tests showed a diminished glycolysis in the group with renal disease suggesting a deficiency in liver glycogen storage. In addition,
Cohen BD, Spritz N, Rubin AL, et al. Hyperguanidemia and Hypoglycemic Unresponsiveness in Renal Disease.. Ann Intern Med. 1961;54:1062. doi: 10.7326/0003-4819-54-5-1062_3
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Published: Ann Intern Med. 1961;54(5):1062.
Cardiology, Coronary Risk Factors, Diabetes, Endocrine and Metabolism, Nephrology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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