W. J. FESSEL, M.R.C.P.; B. W. GRUNBAUM, Ph.D.
Psychotic patients have been shown to have an excessive incidence of rheumatoid factor and lupus factor in their sera.1, 2 This paper reports the electrophoretic serum protein patterns of chronically psychotic patients who had positive serologic tests for rheumatoid factor and the patterns of certain control groups.
A. Patient Material: The following sera of chronically psychotic patients were examined: (1) eighty-four sera known to contain rheumatoid factor (FII-positive group); (2) forty-six sera known not to contain rheumatoid factor or lupus factor (FII-negative group); (3) twenty-six sera, none of them containing the rheumatoid factor, obtained from a group
FESSEL WJ, GRUNBAUM BW. ELECTROPHORETIC AND ANALYTICAL ULTRACENTRIFUGE STUDIES IN SERA OF PSYCHOTIC PATIENTS: ELEVATION OF GAMMA GLOBULINS AND MACROGLOBULINS, AND SPLITTING OF ALPHA2 GLOBULINS*†. Ann Intern Med. 1961;54:1134–1145. doi: https://doi.org/10.7326/0003-4819-54-6-1134
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Published: Ann Intern Med. 1961;54(6):1134-1145.
Endocrine and Metabolism, Infectious Disease, Rheumatology.
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