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ACP Journal Club |19 August 2008

Nondiabetic maternal hyperglycemia was associated with adverse pregnancy outcomes

Anna P. Kenyon, MBChB, MD; Andrew H. Shennan, MBBS, MD

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The HAPO Study Cooperative Research Group. Hyperglycemia and adverse pregnancy outcomes. N Engl J Med. 2008;358:1991-2002. 18463375

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Endocrinology:

See alsoMetformin (alone or with insulin) was as effective as insulin for preventing perinatal complications in gestational diabetes
The 2003 UK National Institute for Health and Clinical Excellence (NICE) guideline for routine prenatal care stated that “current evidence does not support routine screening for gestational diabetes.” The basis of this statement was the uncertainty of glucose thresholds associated with morbidity and the lack of evidence of interventions to improve outcome.
The randomized Australian Carbohydrate Intolerance Study in Pregnant Women (ACHOIS)...
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Kenyon AP, Shennan AH. Nondiabetic maternal hyperglycemia was associated with adverse pregnancy outcomes. Ann Intern Med. 2008;149:JC2–6. doi: 10.7326/0003-4819-149-4-200808190-02006

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Published: Ann Intern Med. 2008;149(4):JC2-6.

DOI: 10.7326/0003-4819-149-4-200808190-02006

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