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ACP Journal Club |15 September 2009

Review: Aspirin reduces vascular events but increases bleeding in primary and secondary prevention

Debabrata Mukherjee, MD, MS

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Baigent C, Blackwell L, Collins R, et al. Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials. Lancet. 2009;373:1849-60. 19482214

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See alsoReview: Aspirin does not reduce CV events but may reduce nonfatal stroke in peripheral artery disease
Aspirin, first synthesized in 1853 by Charles Frederic Gerhardt, a French chemist, has been widely recommended in recent years for the reduction of adverse CV events. Several studies and previous meta-analyses have suggested that aspirin has substantial benefit in the secondary prevention of CV events (1), but the...
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Mukherjee D. Review: Aspirin reduces vascular events but increases bleeding in primary and secondary prevention. Ann Intern Med. 2009;151:JC3–4. doi: 10.7326/0003-4819-151-6-200909150-02004

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Published: Ann Intern Med. 2009;151(6):JC3-4.

DOI: 10.7326/0003-4819-151-6-200909150-02004

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