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ACP Journal Club |15 September 2009

Ultrasonography-guided oral anticoagulant therapy reduced recurrent venous thromboembolism

Henri Bounameaux, MD

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Prandoni P, Prins MH, Lensing AW, et al. Residual thrombosis on ultrasonography to guide the duration of anticoagulation in patients with deep venous thrombosis: a randomized trial. Ann Intern Med. 2009;150:577-85. 19414836

Hematol/Thrombo:

Pulmonology:

Prandoni and colleagues found that fixed-duration OAT was associated with more VTE recurrences than flexible-duration OAT (17% vs 12%). Although other trials have suggested a potential role for repeated ultrasonography to stratify patients by recurrence risk, 2 large cohort studies have not supported this conclusion (1, 2). It may be premature to use residual vein obstruction (RVO) status on repeated ultrasonography to determine OAT duration...
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Bounameaux H. Ultrasonography-guided oral anticoagulant therapy reduced recurrent venous thromboembolism. Ann Intern Med. 2009;151:JC3–9. doi: 10.7326/0003-4819-151-6-200909150-02009

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Published: Ann Intern Med. 2009;151(6):JC3-9.

DOI: 10.7326/0003-4819-151-6-200909150-02009

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