Skip Navigation
Menu
ACP Journal Club |20 July 2010

Review: Enteral nutrition reduces mortality, multiple organ failure, and systemic infection more than TPN in acute pancreatitis

Shahnaz Sultan, MD, MHSc; Chris E. Forsmark, MD

Article, Author, and Disclosure Information
FULL TEXT
Al-Omran M, Albalawi ZH, Tashkandi MF, Al-Ansary LA. Enteral versus parenteral nutrition for acute pancreatitis. Cochrane Database Syst Rev. 2010;(1):CD002837. 20091534

Hospitalists:

Gastroenterology:

Evidence accumulating over the past 2 decades suggests that EN is safer and more effective than TPN for providing nutrition to patients with acute pancreatitis. In the methodologically rigorous Cochrane review and meta-analysis, Al-Omran and colleagues found that EN was associated with a 50% relative risk reduction in mortality compared with TPN. This translates to a number-needed-to-treat of 13. Further, they found reductions in MOF, systemic infection, and operative intervention with EN compared with TPN.
However, the...
FULL TEXT
PDF
Not Available
Citations
Citation

Sultan S, Forsmark CE. Review: Enteral nutrition reduces mortality, multiple organ failure, and systemic infection more than TPN in acute pancreatitis. Ann Intern Med. 2010;153:JC1–6. doi: https://doi.org/10.7326/0003-4819-153-2-201007200-02006

Download citation file:

© 2019

×
Permissions

Published: Ann Intern Med. 2010;153(2):JC1-6.

DOI: 10.7326/0003-4819-153-2-201007200-02006

2 Citations

Related Articles
Sepsis, the Sepsis Syndrome, Multi-Organ Failure: A Plea for Comparable Definitions
Annals of Internal Medicine; 114 (4): 332-333
Annals for Educators - 4 October 2016
Annals of Internal Medicine; 165 (7): ED7
Acute Pancreatitis: How Soon Should We Feed Patients?
Annals of Internal Medicine; 166 (12): 903-904
Annals On Call - Diagnosing Sepsis: Untangling Confusion Around qSOFA and SIRS
Annals of Internal Medicine; 169 (7): OC1
View MoreView Less

Journal Club
Review: In adult inpatients with mild or moderate acute pancreatitis, early feeding may reduce length of stay
Annals of Internal Medicine; 167 (8): JC44
Short-term use of oral corticosteroids was linked to increased risk for sepsis, VTE, and fractures
Annals of Internal Medicine; 167 (4): JC20
Pooled RCTs: In sepsis, continuous (vs intermittent) antibiotic infusion reduced hospital mortality
Annals of Internal Medicine; 166 (4): JC19
Incretin use was not associated with increased risk for acute pancreatitis
Annals of Internal Medicine; 162 (12): JC12
View MoreView Less

Related Point of Care
Acute Pancreatitis
Annals of Internal Medicine; 153 (9): ITC5-1
View MoreView Less

Related Topics
Gastroenterology/Hepatology
Infectious Disease
Multi-Organ Failure and Sepsis
Pancreatic Disease
Pulmonary/Critical Care

Gastroenterology/Hepatology, Infectious Disease, Multi-Organ Failure and Sepsis, Pancreatic Disease, Pulmonary/Critical Care.

PubMed Articles
Ulinastatin Reduces the Severity of Intestinal Damage in the Neonatal Rat Model of Necrotizing Enterocolitis.
Med Sci Monit 2019;25():9123-9130.
IL-27 is elevated in sepsis with acute hepatic injury and promotes hepatic damage and inflammation in the CLP model.
Cytokine 2019;
View More

Results provided by: PubMed

CONTINUE WITH LIMITED ACCESS
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
acp link acp
silverchair link silverchair

Copyright © 2019 American College of Physicians. All Rights Reserved.

Print ISSN: 0003-4819 | Online ISSN: 1539-3704

Privacy Policy

|

Conditions of Use

This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy. | Accept
×

You need a subscription to this content to use this feature.

×
PDF Downloads Require Access to the Full Article.
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
Access to this Free Content Requires Users to be Registered and Logged In. Please Choose One of the Following Options
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×