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ACP Journal Club |18 October 2011

Outpatient treatment was noninferior to inpatient treatment for preventing recurrent VTE in low-risk patients with acute PE

Shannon M. Bates, MD; Gordon H. Guyatt, MD

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Emergency Med:

Hospitalists:

Hematol/Thrombo:

Aujesky D, Roy PM, Verschuren F, et al. Outpatient versus inpatient treatment for patients with acute pulmonary embolism: an international, open-label, randomised, non-inferiority trial. Lancet. 2011;378:41-8. 21703676

Emergency Med:

Hospitalists:

Hematol/Thrombo:

Outpatient treatment of DVT is efficacious, safe, and cost-effective (1), and most patients with DVT are now treated entirely out-of-hospital. The results of several cohort studies suggest that outpatient therapy of PE may be safe in selected, low-risk patients (2); however, an earlier randomized trial comparing early discharge with standard in-hospital treatment of low-risk PE was terminated early because of a higher-than-expected mortality...
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Bates SM, Guyatt GH. Outpatient treatment was noninferior to inpatient treatment for preventing recurrent VTE in low-risk patients with acute PE. Ann Intern Med. 2011;155:JC4–2. doi: 10.7326/0003-4819-155-8-201110180-02002

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Published: Ann Intern Med. 2011;155(8):JC4-2.

DOI: 10.7326/0003-4819-155-8-201110180-02002

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