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ACP Journal Club |15 November 2011

Review: Cholecalciferol (vitamin D3) reduces mortality in adults; other forms of vitamin D do not

Harvey J. Murff, MD, MPH

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Bjelakovic G, Gluud LL, Nikolova D, et al. Vitamin D supplementation for prevention of mortality in adults. Cochrane Database Syst Rev. 2011;(7):CD007470. 21735411

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Adequate levels of vitamin D are important for bone health. Inconsistent data suggesting a beneficial role of vitamin D on nonskeletal health outcomes have, however, led to aggressive supplementation. The Institute of Medicine (IOM) concluded that the prevalence of vitamin D deficiency in the USA has often been overestimated, and a serum 25-hydroxyvitamin D level of 20 ng/mL (50 nmol/L) should be adequate for ≥ 97.5% of the population (1).
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Murff HJ. Review: Cholecalciferol (vitamin D3) reduces mortality in adults; other forms of vitamin D do not. Ann Intern Med. 2011;155:JC5–4. doi: 10.7326/0003-4819-155-10-201111150-02004

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Published: Ann Intern Med. 2011;155(10):JC5-4.

DOI: 10.7326/0003-4819-155-10-201111150-02004

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