THOMAS P. LOUGHRAN Jr., M.D.; MARSHALL E. KADIN, M.D.; H. JOACHIM DEEG, M.D.
A patient with a long history of celiac sprue developed a pleomorphic intestinal lymphoma. Cell suspensions of tumor cells and immunoperoxidase labeling of cell surface antigens in frozen tissue sections clearly showed the lymphoma to be of T-cell origin, despite the presence of other nontumor cells bearing enzyme markers of histiocytes. These findings may have important implications on the cellular origin of lymphomas developing in patients with celiac sprue.
LOUGHRAN TP, KADIN ME, DEEG HJ. T-Cell Intestinal Lymphoma Associated with Celiac Sprue. Ann Intern Med. ;104:44–47. doi: 10.7326/0003-4819-104-1-44
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Published: Ann Intern Med. 1986;104(1):44-47.
Celiac Disease and Malabsorption, Gastroenterology/Hepatology, Hematology/Oncology, Leukemia/Lymphoma.
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