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ACP Journal Club |17 April 2012

Radical prostatectomy and watchful waiting for localized prostate cancer did not differ for quality of life

Allan V. Prochazka, MD, MSc; Tanner J. Caverly, MD

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Johansson E, Steineck G, Holmberg L, et al. Long-term quality-of-life outcomes after radical prostatectomy or watchful waiting: the Scandinavian Prostate Cancer Group-4 randomised trial. Lancet Oncol. 2011;12:891-9. 21821474

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SPCG-4 found an all-cause mortality benefit with radical prostatectomy compared with watchful waiting in men with clinically detected, early-stage prostate cancer (1). The report by Johansson and colleagues further informs decision-making, but like the earlier study report (1) it has limited applicability in the modern era of prostate-specific antigen (PSA)–detected prostate cancer because only 5% of men in SPCG-4 had nonclinically evident PSA-detected cancer (88% had...
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Prochazka AV, Caverly TJ. Radical prostatectomy and watchful waiting for localized prostate cancer did not differ for quality of life. Ann Intern Med. 2012;156:JC4–3. doi: https://doi.org/10.7326/0003-4819-156-8-201204170-02003

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Published: Ann Intern Med. 2012;156(8):JC4-3.

DOI: 10.7326/0003-4819-156-8-201204170-02003

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