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ACP Journal Club |17 July 2012

Review: Daily aspirin reduces short-term risk for cancer and cancer mortality

Andrew K. Diehl, MD, MSc

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Rothwell PM, Price JF, Fowkes FG, et al. Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials. Lancet. 2012;379:1602-12. 22440946

GIM/FP/GP:

Cardiology:

Oncology:

The idea of taking a pill at breakfast to prevent cancer may seem futuristic, although raloxifene and tamoxifen are currently approved by the US Food and Drug Administration for prevention of invasive breast cancer. Beginning more than 2 decades ago, animal models, case–control studies, cohort studies, and RCTs in high-risk populations suggested that regular use of aspirin or nonsteroidal antiinflammatory...
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Diehl AK. Review: Daily aspirin reduces short-term risk for cancer and cancer mortality. Ann Intern Med. 2012;157:JC1–2. doi: 10.7326/0003-4819-157-2-201207170-02002

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Published: Ann Intern Med. 2012;157(2):JC1-2.

DOI: 10.7326/0003-4819-157-2-201207170-02002

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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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