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ACP Journal Club |20 November 2012

Fractional flow reserve–guided PCI reduced urgent revascularization at 7 months in coronary artery disease

Jay N. Cohn, MD

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De Bruyne B, Pijls NH, Kalesan B, et al; FAME 2 Trial Investigators. Fractional flow reserve-guided PCI versus medical therapy in stable coronary disease. N Engl J Med. 2012;367:991-1001. 22924638

Cardiology:

It is well-established that PCI in patients with stable but symptomatic coronary artery disease relieves angina and improves quality of life without reducing risk for acute MI or death compared with MT (1). Despite this evidence, advocates for PCI continue to search for improvements in methodology or patient selection that could show that revascularization of significantly stenotic lesions improves prognosis.
The FAME 1 study showed that FFR-guided...
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Cohn JN. Fractional flow reserve–guided PCI reduced urgent revascularization at 7 months in coronary artery disease. Ann Intern Med. 2012;157:JC5–9. doi: 10.7326/0003-4819-157-10-201211200-02009

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Published: Ann Intern Med. 2012;157(10):JC5-9.

DOI: 10.7326/0003-4819-157-10-201211200-02009

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