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ACP Journal Club |18 December 2012

Review: Statins reduce pancreatitis in adults with normal or mildly elevated triglyceride levels

Hanna E. Bloomfield, MD, MPH

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Preiss D, Tikkanen MJ, Welsh P, et al. Lipid-modifying therapies and risk of pancreatitis: a meta-analysis. JAMA. 2012;308:804-11. 22910758

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The high-quality meta-analysis by Preiss and colleagues showed that statins were associated with a lower risk for pancreatitis, a finding that is, at best, hypothesis-generating. None of the included trials were explicitly designed to examine the association between statin use and pancreatitis, and none had clearly standardized methods for identifying and adjudicating cases. Indeed, data for incident pancreatitis were published in only 2 trials; information from the other 19 was solicited from the trialists. The finding about...
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Bloomfield HE. Review: Statins reduce pancreatitis in adults with normal or mildly elevated triglyceride levels. Ann Intern Med. 2012;157:JC6–8. doi: 10.7326/0003-4819-157-12-201212180-02008

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Published: Ann Intern Med. 2012;157(12):JC6-8.

DOI: 10.7326/0003-4819-157-12-201212180-02008

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Related Topics
Cardiology
Coronary Risk Factors
Dyslipidemia
Gastroenterology/Hepatology
Pancreatic Disease

Cardiology, Coronary Risk Factors, Dyslipidemia, Gastroenterology/Hepatology, Pancreatic Disease.

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