Skip Navigation
Menu
ACP Journal Club |19 March 2013

Amoxicillin/clavulanate vs placebo: more exacerbation cures, fewer recurrences in mild-to-moderate COPD

Sandra G. Adams, MD, MS; Jay I. Peters, MD

Article, Author, and Disclosure Information
FULL TEXT
Llor C, Moragas A, Hernández S, Bayona C, Miravitlles M. Efficacy of antibiotic therapy for acute exacerbations of mild to moderate chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2012;186:716-23. 22923662

GIM/FP/GP:

Hospitalists:

Pulmonology:

The well-done RCT by Llor and colleagues studied an unresolved clinical question: What is the role of antibiotics in outpatients with acute exacerbations of COPD? The study clearly showed that the antibiotic group had higher rates of improvement and/or cure and a longer median time to the next exacerbation. It uniquely adds to the literature because it studied a well-defined population managed in a...
FULL TEXT
PDF
Not Available
Citations
Citation

Adams SG, Peters JI. Amoxicillin/clavulanate vs placebo: more exacerbation cures, fewer recurrences in mild-to-moderate COPD. Ann Intern Med. 2013;158:JC3. doi: https://doi.org/10.7326/0003-4819-158-6-201303190-02003

Download citation file:

© 2019

×
Permissions

Published: Ann Intern Med. 2013;158(6):JC3.

DOI: 10.7326/0003-4819-158-6-201303190-02003

0 Citations

Related Articles
Review: ≤ 7 and > 7 days of systemic corticosteroids do not differ for efficacy in COPD exacerbations
Annals of Internal Medicine; 162 (6): JC7
Update in Pulmonary Medicine: Evidence Published in 2015
Annals of Internal Medicine; 164 (9): W55-W60
Update in Pulmonary Medicine: Evidence Published in 2014
Annals of Internal Medicine; 162 (9): W117-W121
5 days of prednisone was noninferior to 14 days in patients with acute COPD exacerbation
Annals of Internal Medicine; 159 (6): JC5
View MoreView Less

Journal Club
Review: ≤ 7 and > 7 days of systemic corticosteroids do not differ for efficacy in COPD exacerbations
Annals of Internal Medicine; 162 (6): JC7
5 days of prednisone was noninferior to 14 days in patients with acute COPD exacerbation
Annals of Internal Medicine; 159 (6): JC5
In symptomatic COPD, once-daily triple vs dual therapy reduced moderate or severe exacerbations at 1 year
Annals of Internal Medicine; 169 (4): JC16
In COPD, long-term use of higher doses of inhaled corticosteroids was linked to increased fracture risk
Annals of Internal Medicine; 168 (12): JC71
View MoreView Less

Related Point of Care
Chronic Obstructive Pulmonary Disease
Annals of Internal Medicine; 154 (7): ITC4-1
Chronic Obstructive Pulmonary Disease
Annals of Internal Medicine; 148 (5): ITC3-1
View MoreView Less

Related Topics
Chronic Obstructive Airway Disease
Pulmonary/Critical Care

Chronic Obstructive Airway Disease, Pulmonary/Critical Care.

PubMed Articles
Time-updated resting heart rate predicts mortality in patients with COPD.
Clin Res Cardiol 2019.
Unique synergistic antiviral effects of Shufeng Jiedu Capsule and oseltamivir in influenza A viral-induced acute exacerbation of chronic obstructive pulmonary disease.
Biomed Pharmacother 2019;
View More

Results provided by: PubMed

CONTINUE WITH LIMITED ACCESS
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
acp link acp
silverchair link silverchair

Copyright © 2019 American College of Physicians. All Rights Reserved.

Print ISSN: 0003-4819 | Online ISSN: 1539-3704

Privacy Policy

|

Conditions of Use

This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy. | Accept
×

You need a subscription to this content to use this feature.

×
PDF Downloads Require Access to the Full Article.
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
Access to this Free Content Requires Users to be Registered and Logged In. Please Choose One of the Following Options
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×