Skip Navigation
Menu
ACP Journal Club |20 August 2013

Patent foramen ovale closure and medical therapy did not differ for recurrence after cryptogenic embolism

Mukul Sharma, MD

Article, Author, and Disclosure Information
FULL TEXT
Meier B, Kalesan B, Mattle HP, et al: PC Trial Investigators. Percutaneous closure of patent foramen ovale in cryptogenic embolism. N Engl J Med. 2013;368:1083-91. 23514285

Cardiology:

Neurology:

Is closure of patent foramen ovale (PFO) better than medical therapy alone for reducing recurrence after cryptogenic embolism?
Randomized controlled trial (Clinical Trial Comparing Percutaneous Closure of Patent Foramen Ovale [PFO] Using the Amplatzer PFO Occluder with Medical Treatment in Patients with Cryptogenic Embolism [PC Trial]). ClinicalTrials.gov NCT00166257.
Concealed.*
Blinded* (outcome adjudication committee).
5 years (mean 4 y).
29 centers in Australia, Brazil, Canada, and Europe.
414 patients < 60 years of...
FULL TEXT
PDF
Not Available
Citations
Citation

Sharma M. Patent foramen ovale closure and medical therapy did not differ for recurrence after cryptogenic embolism. Ann Intern Med. 2013;159:JC5. doi: 10.7326/0003-4819-159-4-201308200-02005

Download citation file:

© 2019

×
Permissions

Published: Ann Intern Med. 2013;159(4):JC5.

DOI: 10.7326/0003-4819-159-4-201308200-02005

0 Citations

Related Articles
Review: In cryptogenic stroke with PFO, adding PFO closure to medical therapy reduces recurrence
Annals of Internal Medicine; 168 (8): JC43
Device Closure Versus Medical Therapy Alone for Patent Foramen Ovale in Patients With Cryptogenic Stroke: A Systematic Review and Meta-analysis
Annals of Internal Medicine; 168 (5): 335-342
Percutaneous Closure Versus Medical Treatment in Stroke Patients With Patent Foramen Ovale: A Systematic Review and Meta-analysis
Annals of Internal Medicine; 168 (5): 343-350
Patent foramen ovale closure and medical therapy did not differ for recurrence after cryptogenic stroke
Annals of Internal Medicine; 159 (4): JC4
View MoreView Less

Journal Club
Review: In cryptogenic stroke with PFO, adding PFO closure to medical therapy reduces recurrence
Annals of Internal Medicine; 168 (8): JC43
Patent foramen ovale closure and medical therapy did not differ for recurrence after cryptogenic stroke
Annals of Internal Medicine; 159 (4): JC4
Review: Evidence is inconclusive on metabolic surgery vs medical treatment for microvascular complications in T2DM
Annals of Internal Medicine; 169 (2): JC9
In AF and HF, catheter ablation vs medical therapy reduced mortality and hospitalization for worsening HF
Annals of Internal Medicine; 168 (10): JC55
View MoreView Less

Related Topics
Cardiology
Neurology
Stroke

Cardiology, Neurology, Stroke.

PubMed Articles
Being fully digital: Perspective of a Dutch academic pathology lab.
Histopathology 2019.
Definitions, adjudication, and reporting of pulmonary embolism-related death in clinical studies: a systematic review.
J Thromb Haemost 2019.
View More

Results provided by: PubMed

CONTINUE WITH LIMITED ACCESS
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
acp link acp
silverchair link silverchair

Copyright © 2019 American College of Physicians. All Rights Reserved.

Print ISSN: 0003-4819 | Online ISSN: 1539-3704

Privacy Policy

|

Conditions of Use

This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy. | Accept
×

You need a subscription to this content to use this feature.

×
PDF Downloads Require Access to the Full Article.
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
Access to this Free Content Requires Users to be Registered and Logged In. Please Choose One of the Following Options
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×