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ACP Journal Club |20 August 2013

A 12-month, in-home exercise program delayed functional deterioration in Alzheimer disease

Calvin Hirsch, MD, FACP

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Pitkälä KH, Pöysti MM, Laakkonen ML, et al. Effects of the Finnish Alzheimer Disease Exercise Trial (FINALEX): A randomized controlled trial. JAMA Intern Med. 2013:173:894-901. 23589097

GIM/FP/GP:

Geriatrics:

Neurology:

Phys Med & Rehab:

Does long-term exercise delay deterioration of physical functioning and mobility in patients with Alzheimer disease (AD) who live at home?
Randomized controlled trial (Finnish Alzheimer Disease Exercise [FINALEX] trial). Australian New Zealand Clinical Trials Registry ACTRN 12608000037303.
Concealed.*
Unblinded.*
12 months.
Finland.
210 patients ≥ 65 years of age (mean age 78 y, 61% men) and their spousal caregivers (mean age 76 y, 61% women). Patients had AD diagnosed by a geriatrician or neurologist; lived at home with their spouse; could walk independently; had ≥ 1 of decreased walking speed, ≥ 1 fall in the past year, or unintentional weight loss; and did not have a terminal disease.
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Hirsch C. A 12-month, in-home exercise program delayed functional deterioration in Alzheimer disease. Ann Intern Med. ;159:JC10. doi: 10.7326/0003-4819-159-4-201308200-02010

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Published: Ann Intern Med. 2013;159(4):JC10.

DOI: 10.7326/0003-4819-159-4-201308200-02010

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