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Letters |17 December 2013

Vitamin D and Calcium Supplementation to Prevent Fractures in Adults

Toshihiro Sugiyama, MD, PhD

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Author, Article, and Disclosure Information
  • From Yamaguchi University School of Medicine, Yamaguchi, Japan.

    Potential Conflicts of Interest: None disclosed.

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TO THE EDITOR:
The guideline from the U.S. Preventive Services Task Force (USPSTF) (1) concludes that the current evidence about calcium and vitamin D supplementation to prevent fractures in adults is essentially insufficient. This statement may be partly based on the limited efficacy of calcium and vitamin D supplementation in preventing fractures from skeletal adaptation to mechanical loading, although vitamin D promotes calcium absorption in the gut and supports bone mineralization that is essential for skeletal stiffness.
Bone responds to the local mechanical environment at each skeletal site, as evidenced by marked bone gain in the dominant arms of professional...
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Sugiyama T. Vitamin D and Calcium Supplementation to Prevent Fractures in Adults. Ann Intern Med. 2013;159:856. doi: https://doi.org/10.7326/0003-4819-159-12-201312170-00014

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Published: Ann Intern Med. 2013;159(12):856.

DOI: 10.7326/0003-4819-159-12-201312170-00014

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