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Letters |17 December 2013

Methylprednisolone Injections for the Carpal Tunnel Syndrome

Francisco Ramirez-Lafita, MD, PhD

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TO THE EDITOR:
Atroshi and colleagues’ study (1) shows temporary but nonpersistent relief of the carpal tunnel syndrome (CTS) after local methylprednisolone injections. In fact, after week 36, the number of patients treated with methylprednisolone injections who had surgery increased (between 73% and 81% at the end of the first year). Moreover, secondary end points (such as the short Disabilities of the Arm, Shoulder and Hand score; Short Form-36 Health Survey bodily pain score; and Short Form-6D score) and treatment satisfaction showed no differences between methylprednisolone and placebo after 10 weeks of corticosteroid injections.
Recent studies have found different outcomes. A study (2) comparing local corticosteroid injections with surgical decompression showed that both treatments effectively alleviated symptoms at 2-year follow-up: 60% of patients who received corticosteroid injections versus 69% of patients who had surgery showed a 20% decrease in nocturnal paresthesia.
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Ramirez-Lafita F. Methylprednisolone Injections for the Carpal Tunnel Syndrome. Ann Intern Med. ;159:857–858. doi: 10.7326/0003-4819-159-12-201312170-00018

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Published: Ann Intern Med. 2013;159(12):857-858.

DOI: 10.7326/0003-4819-159-12-201312170-00018

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