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Letters |6 May 2014

Vitamin and Mineral Supplements in the Primary Prevention of Cardiovascular Disease and Cancer

Mark J. Bolland, MBChB, PhD; Andrew Grey, MD; Ian R. Reid, MD

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Fortmann and colleagues (1) identified 5 randomized, controlled trials (RCTs) of calcium or vitamin D supplements and cardiovascular disease and cancer. Data were available on all-cause mortality for 3 RCTs of calcium, 1 RCT of vitamin D, and 1 RCT of calcium and vitamin D; cardiovascular disease incidence for 1 RCT of calcium, 2 RCTs of vitamin D, and 1 RCT of calcium and vitamin D; and cancer incidence for 3 RCTs of calcium, 2 RCTs of vitamin D, and 1 RCT of calcium and vitamin D.
In previous systematic reviews of calcium supplementation, we identified 8...
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Bolland MJ, Grey A, Reid IR. Vitamin and Mineral Supplements in the Primary Prevention of Cardiovascular Disease and Cancer. Ann Intern Med. 2014;160:655–656. doi: 10.7326/L14-5009-4

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Published: Ann Intern Med. 2014;160(9):655-656.

DOI: 10.7326/L14-5009-4

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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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