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Editorials |18 November 2014

Comparative Effectiveness of Pharmacologic Treatments to Prevent Fractures: Is This All We Need to Know?

Heike A. Bischoff-Ferrari, MD, DrPH; Otto Meyer, MD

Article, Author, and Disclosure Information
Author, Article, and Disclosure Information
This article was published online first at www.annals.org on 9 September 2014.
  • From Geriatric Clinic, University Hospital Zurich, Centre on Aging and Mobility, University of Zurich, and City Hospital Waid, Zurich, Switzerland.

    Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M14-1942.

    Requests for Single Reprints: Heike A. Bischoff-Ferrari, MD, DrPH, Geriatric Clinic, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland; e-mail, Heike.Bischoff@usz.ch.

    Current Author Addresses: Drs. Bischoff-Ferrari and Meyer: Geriatric Clinic, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland.

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Nearly 75% of all osteoporotic fractures occur among adults aged 65 years or older, contributing significantly to illness and death in the senior population. After age 75 years, hip fractures are the most frequent, and severe fractures cause permanent functional impairment in 50%, loss of autonomy in 30%, and death in 15% to 20% of cases. The exponential increase in hip fractures after age 75 years translates into an estimated 1 in 3 women and 1 in 6 men who will have a hip fracture by their 90th year. Likewise, other osteoporotic fractures, including those of the spine, show a steep increase with age (1).
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Bischoff-Ferrari HA, Meyer O. Comparative Effectiveness of Pharmacologic Treatments to Prevent Fractures: Is This All We Need to Know?. Ann Intern Med. ;161:755–756. doi: 10.7326/M14-1942

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Published: Ann Intern Med. 2014;161(10):755-756.

DOI: 10.7326/M14-1942

4 Citations

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