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ACP Journal Club |16 September 2014

In newly diagnosed type 2 diabetes mellitus, a Mediterranean diet (vs a low-fat diet) delayed start of glucose-lowering drugs

Eugene C. Corbett Jr., MD, MACP

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Esposito K, Maiorino MI, Petrizzo M, Bellastella G, Giugliano D. The effects of a Mediterranean diet on need for diabetes drugs and remission of newly diagnosed type 2 diabetes: Follow-up of a randomized trial. Diabetes Care. 2014;37:1824-30. 24722497

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In newly diagnosed type 2 diabetes, does a low-carbohydrate Mediterranean diet (LCMD) delay the start of glucose-lowering medication compared with a low-fat diet (LFD)?
Extended follow-up of a randomized controlled trial. ClinicalTrials.gov NCT00725257.
{Concealed}*.†
Blinded† (outcome assessors).
8.1 years for the primary outcome.
{Diabetes clinic in a university hospital in Naples, Italy}*.
215 patients {30 to 75 years of age}* (mean age 52 y, 51% women) who had newly diagnosed type 2 diabetes, {body mass index > 25 kg/m2, hemoglobin A1c [HbA1c] level < 11%}*, and no previous treatment with glucose-lowering medications.
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Corbett Jr. EC. In newly diagnosed type 2 diabetes mellitus, a Mediterranean diet (vs a low-fat diet) delayed start of glucose-lowering drugs. Ann Intern Med. 2014;161:JC4. doi: 10.7326/0003-4819-161-6-201409160-02004

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Published: Ann Intern Med. 2014;161(6):JC4.

DOI: 10.7326/0003-4819-161-6-201409160-02004

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