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Letters |16 December 2014

HIV Infection and Subclinical Coronary Atherosclerosis

Wendy S. Post, MD, MS; Richard T. George, MD; Matthew Budoff, MD

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We thank Dr. Chartrand-Lefebvre and colleagues for their insightful comments about our article, which showed that HIV-infected men had a greater prevalence of and more extensive noncalcified plaque than uninfected men in MACS (Multicenter AIDS Cohort Study). We agree that the noninvasive assessment plaque vulnerability with CT scanning may further elucidate potential mechanisms that place HIV-infected persons at increased risk for acute myocardial infarction. Before plaque rupture, the degree of luminal stenosis is frequently less than 50% and therefore would not lead to symptoms or abnormal results on stress testing (1). Recent advances in the analysis...
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Post WS, George RT, Budoff M. HIV Infection and Subclinical Coronary Atherosclerosis. Ann Intern Med. 2014;161:923–924. doi: 10.7326/L14-5033-2

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Published: Ann Intern Med. 2014;161(12):923-924.

DOI: 10.7326/L14-5033-2

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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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