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Letters |21 April 2015

Pregnancy After Spontaneous Coronary Artery Dissection: A Case Series

Marysia S. Tweet, MD; Sharonne N. Hayes, MD; Rajiv Gulati, MD, PhD; Carl H. Rose, MD; Patricia J.M. Best, MD

Article, Author, and Disclosure Information
Author, Article, and Disclosure Information
  • From Mayo Clinic College of Medicine, Rochester, Minnesota.

    Acknowledgment: The authors thank the patients participating in the Mayo Clinic SCAD Registry and acknowledge Jill Boyum; Michelle Schoeppner; Diane Vrieze; and Sue Ward, RN, for their registry work.

    Financial Support: This study was funded in part by the Mayo Clinic Division of Cardiovascular Diseases, Chicago Mercantile Exchange Foundation, and SCAD Research, Inc.

    Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L14-0446.

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Background: Spontaneous coronary artery dissection (SCAD) is an increasingly recognized and potentially fatal cause of myocardial infarction (MI) that predominantly affects young women (1, 2). Pregnancy is considered a contributory factor in approximately 12% to 30% of events (1, 3, 4) and recurrence is now recognized, with 10-year Kaplan–Meier estimated rates as high as 29% (1). Current recommendations to avoid pregnancy after SCAD are based on the presumed increased risk for recurrence with pregnancy, although, to our knowledge, assessment of pregnancy after SCAD has not been described.
Objective: To determine the risk for subsequent events in patients who became pregnant after SCAD.
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Tweet MS, Hayes SN, Gulati R, Rose CH, Best PJ. Pregnancy After Spontaneous Coronary Artery Dissection: A Case Series. Ann Intern Med. ;162:598–600. doi: 10.7326/L14-0446

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Published: Ann Intern Med. 2015;162(8):598-600.

DOI: 10.7326/L14-0446

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