Skip Navigation
Menu
ACP Journal Club |21 April 2015

Glyceryl trinitrate did not improve functional outcome in patients with acute stroke and high BP

Graeme J. Hankey, MBBS

Article, Author, and Disclosure Information
FULL TEXT
ENOS Trial Investigators. Efficacy of nitric oxide, with or without continuing antihypertensive treatment, for management of high blood pressure in acute stroke (ENOS): a partial-factorial randomised controlled trial. Lancet. 2015;385:617-28. 25465108

Hospitalists:

Cardiology:

Geriatrics:

Neurology:

In patients with acute stroke and high blood pressure (BP), does glyceryl trinitrate (nitric oxide) safely improve outcomes? What are the effects of continuing versus stopping antihypertensive drugs?
Partial 2 x 2 factorial, randomized, controlled trial (RCT) (Efficacy of Nitric Oxide in Stroke [ENOS] trial). Current Controlled Trials ISRCTN99414122.
Concealed.*
Blinded* (for glyceryl trinitrate: patients, data collectors, and outcome assessors; for antihypertensive drugs: data collectors...
FULL TEXT
PDF
Not Available
Citations
Citation

Hankey GJ. Glyceryl trinitrate did not improve functional outcome in patients with acute stroke and high BP. Ann Intern Med. 2015;162:JC12. doi: https://doi.org/10.7326/ACPJC-2015-162-8-012

Download citation file:

© 2019

×
Permissions

Published: Ann Intern Med. 2015;162(8):JC12.

DOI: 10.7326/ACPJC-2015-162-8-012

0 Citations

Related Articles
The Response of Metabolic Alkalosis in Severe Hypertension to Antihypertensive Drugs
Annals of Internal Medicine; 58 (2): 336-340
Late thrombectomy reduced disability in acute stroke with mismatched clinical deficit and infarction volume
Annals of Internal Medicine; 168 (4): JC17
In acute ischemic stroke, rapid intraarterial treatment plus usual care improved functional independence
Annals of Internal Medicine; 162 (10): JC3
In acute ischemic stroke, early intraarterial treatment plus usual care improved functional independence
Annals of Internal Medicine; 162 (10): JC2
View MoreView Less

Journal Club
Late thrombectomy reduced disability in acute stroke with mismatched clinical deficit and infarction volume
Annals of Internal Medicine; 168 (4): JC17
In acute ischemic stroke, rapid intraarterial treatment plus usual care improved functional independence
Annals of Internal Medicine; 162 (10): JC3
In acute ischemic stroke, early intraarterial treatment plus usual care improved functional independence
Annals of Internal Medicine; 162 (10): JC2
Correction to ACP Journal Club: Guideline—The AHA/ASAmade 217 recommendations for early management of acute ischemic stroke in adults
Annals of Internal Medicine; 169 (4): JC24
View MoreView Less

Related Point of Care
Hypertension
Annals of Internal Medicine; 170 (9): ITC65-ITC80
Hypertension
Annals of Internal Medicine; 161 (11): ITC1
Hypertension
Annals of Internal Medicine; 149 (11): ITC6-1
Stable Ischemic Heart Disease
Annals of Internal Medicine; 171 (3): ITC17-ITC32
View MoreView Less

Related Topics
Cardiology
Coronary Risk Factors
Hypertension
Nephrology
Neurology

Cardiology, Coronary Risk Factors, Hypertension, Nephrology, Neurology.

PubMed Articles
Effects of road traffic noise on the prevalence of cardiovascular diseases: The case of Thessaloniki, Greece.
Sci Total Environ 2019;
Assessment of cardiac risk in chronic asymptomatic alcoholics using blood pressure and electrocardiogram, and the relation with duration of drinking.
J Basic Clin Physiol Pharmacol 2019.
View More

Results provided by: PubMed

CONTINUE WITH LIMITED ACCESS
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
acp link acp
silverchair link silverchair

Copyright © 2019 American College of Physicians. All Rights Reserved.

Print ISSN: 0003-4819 | Online ISSN: 1539-3704

Privacy Policy

|

Conditions of Use

This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy. | Accept
×

You need a subscription to this content to use this feature.

×
PDF Downloads Require Access to the Full Article.
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
Access to this Free Content Requires Users to be Registered and Logged In. Please Choose One of the Following Options
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×