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ACP Journal Club |20 October 2015

A risk calculator based on self-reported information predicted 5-year mortality in adults in the UK

Howard S. Kirshner, MD

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Ganna A, Ingelsson E.5 year mortality predictors in 498 103 UK biobank participants: a prospective population-based study. Lancet. 2015 Jun 2. [Epub ahead of print]26049253

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Does a risk calculator based on self-reported information predict 5-year mortality in adults in the UK?
Derivation and validation of a prediction score using data from a population-based cohort study (UK Biobank Study), with linkage to National Health Services databases.
21 assessment centers in England and Wales (derivation cohort) and Scotland (validation cohort).
498 103 adults 37 to 73 years of age (mean age 57 y, 54% women) who enrolled in the UK Biobank study from Apr 2007 to Jul 2010; persons with > 80% missing variables were excluded. The derivation cohort comprised 462 293 patients, and the validation cohort comprised 35 810 patients.
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Kirshner HS. A risk calculator based on self-reported information predicted 5-year mortality in adults in the UK. Ann Intern Med. ;163:JC13. doi: 10.7326/ACPJC-2015-163-8-013

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Published: Ann Intern Med. 2015;163(8):JC13.

DOI: 10.7326/ACPJC-2015-163-8-013

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